Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8960919 | 0.88 | KMT2A (0.56) | KMT2AMEN1HTR7MAPTALOX15 | |
| SCHEMBL6898109 | 0.84 | KMT2A (0.52) | KMT2AMEN1HTR7MAPTALOX15 | |
| SCHEMBL8470559 | 0.83 | KMT2A (0.61) | KMT2AMEN1HTR7MAPTALOX15 | |
| SCHEMBL13640085 | 0.83 | KMT2A (0.61) | KMT2AMEN1HTR7MAPTALOX15 | |
| SCHEMBL5494961 | 0.80 | TDP1 (0.55) | KMT2AMEN1MAPTLMNAPOLB | |
| SCHEMBL15140443 | 0.80 | MEN1 (0.51) | KMT2AMEN1MAPTLMNAPOLB | |
| SCHEMBL11959217 | 0.80 | LMNA (0.58) | KMT2AMEN1MAPTLMNAPOLB | |
| SCHEMBL8348164 | 0.80 | LMNA (0.58) | KMT2AMEN1HTR7MAPTALOX15 | |
| SCHEMBL27898991 | 0.78 | KMT2A (0.56) | KMT2AMEN1HTR7MAPTALOX15 | |
| SCHEMBL12869175 | 0.78 | S1PR1 (0.58) | KMT2AMEN1S1PR1LMNAADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388359-A1 | Imidazoline compounds | CIBA-GEIGY AG (CH) | 1990-09-19 | — | — | EP | disclosed |