SCHEMBL5494961

SCHEMBL5494961

CCOCC(O)COc1ccc(N)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.55
TSHR P16473 2/20 0.55
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
POLB P06746 2/20 0.49
MAPT P10636 2/20 0.49
LMNA P02545 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
ADRB2 P07550 1/20 0.46
ADRB1 P08588 1/20 0.46
ADRB3 P13945 1/20 0.46
CA1 P00915 3/20 0.44
CA2 P00918 3/20 0.44
CA4 P22748 3/20 0.44
CA7 P43166 3/20 0.44
CA9 Q16790 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
ALDH1A1 P00352 2/20 0.44
CYP1A2 P05177 1/20 0.43
PLA2G4B P0C869 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11566950 0.89 MAPT (0.50) TDP1TSHRPOLBMAPTLMNA
SCHEMBL7934862 0.87 MAPT (0.55) TDP1TSHRPOLBMAPTLMNA
SCHEMBL6049252 0.84 TDP1 (0.55) TDP1TSHRPOLBMAPTLMNA
SCHEMBL15140443 0.83 MEN1 (0.51) TDP1TSHRMEN1KMT2APOLB
SCHEMBL28531572 0.82 POLB (0.51) TDP1TSHRPOLBMAPTLMNA
SCHEMBL11959217 0.82 LMNA (0.58) TSHRMEN1KMT2APOLBMAPT
SCHEMBL1263762 0.81 POLB (0.47) TDP1TSHRMEN1KMT2APOLB
SCHEMBL11018105 0.80 KMT2A (0.49) TDP1TSHRMEN1KMT2APOLB
SCHEMBL9248709 0.80 HTT (0.61) TSHRMEN1KMT2APOLBMAPT
SCHEMBL29620622 0.80 LTA4H (0.58) MEN1KMT2APOLBMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109641855-B Azo compounds, polymers, and processes for their preparation and use 东莞东阳光医疗智能器件研发有限公司 2022-04-29 CN disclosed
CN-110382628-B Polymerizable dye compound, preparation method, polymer containing dye and application 东莞东阳光医疗智能器件研发有限公司 2021-03-02 CN disclosed
EP-1295870-B1 SUPLATAST TOSILATE CRYSTALS TAIHO PHARMACEUTICAL CO LTD (JP) 2007-12-19 EP disclosed
US-20030149105-A1 Suplatast tosilate crystals TAIHO PHARMACEUTICAL CO., LTD. (JP) 2003-08-07 US disclosed
US-6593326-B1 Useful as anti-cancer agents; and processes for their manufacture and pharmaceutical compositions containing them are described. Apoptotic effect in a warm-blooded animal such as man. ASTRAZENECA AB (SE) 2003-07-15 US disclosed
EP-1295870-A1 SUPLATAST TOSILATE CRYSTALS TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) 2003-03-26 EP disclosed
EP-0178073-B1 AMIDE COMPOUNDS, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) 1988-04-27 EP disclosed
US-4670583-A ANTIALLERGENS TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) 1987-06-02 US disclosed
EP-0178073-A1 amide compounds, process for preparing the same and pharmaceutical compositions containing the same TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) 1986-04-16 EP disclosed
US-4556737-A ANTIALLERGENS, TREATMENT OF ASTHMA AND RHINITIS TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) 1985-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030149105-A1 Suplatast tosilate crystals SART3, SOST, PRPF19 TDP1 477/4885TSHR 314/4885MEN1 2445/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.