SCHEMBL10356908

SCHEMBL10356908

CCC(C)C(N)CCCCCCCCC(N)C(C)CC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.42
TRPV1 Q8NER1 1/20 0.40
TRPA1 O75762 1/20 0.40
SPHK1 Q9NYA1 2/20 0.39
CYP2D6 P10635 2/20 0.37
TP53 P04637 2/20 0.37
GMNN O75496 1/20 0.37
LMNA P02545 1/20 0.37
POLB P06746 1/20 0.37
THPO P40225 1/20 0.37
MTOR P42345 1/20 0.37
BLM P54132 1/20 0.37
KDM4E B2RXH2 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
MAPT P10636 1/20 0.37
CETP P11597 1/20 0.37
HTT P42858 1/20 0.37
UBE2N P61088 1/20 0.37
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28220782 1.00 OPRM1 (0.42) OPRM1TRPV1TRPA1SPHK1CYP2D6
SCHEMBL27945762 0.97 OPRM1 (0.43) OPRM1TRPV1TRPA1SPHK1CYP2D6
SCHEMBL31131332 0.93 OPRM1 (0.54) OPRM1SPHK1CYP2D6TP53GMNN
SCHEMBL6897233 0.93 OPRM1 (0.54) OPRM1SPHK1CYP2D6TP53GMNN
SCHEMBL11870499 0.93 OPRM1 (0.54) OPRM1SPHK1CYP2D6TP53GMNN
SCHEMBL27726429 0.91 DNM1 (0.40) TRPV1TRPA1SPHK1ALDH1A1
SCHEMBL3834384 0.91 DNM1 (0.40) TRPV1TRPA1SPHK1ALDH1A1
SCHEMBL516695 0.90 OPRM1 (0.56) OPRM1SPHK1CYP2D6TP53GMNN
SCHEMBL18733092 0.87 OPRM1 (0.37) OPRM1TRPV1TRPA1SPHK1ALDH1A1
SCHEMBL20663195 0.86 OPRM1 (0.46) OPRM1SPHK1CYP2D6TP53GMNN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0169807-B1 POLYAMIDE, PROCESS FOR ITS FABRICATION AND ITS USE CIBA-GEIGY AG (CH) 1990-12-05 EP disclosed
US-4617375-A Polyamide, from condensed cyclic dicarboxylic acid and branched chain diamine CIBA-GEIGY CORPORATION (US) 1986-10-14 US disclosed
EP-0000331-B1 METHOD OF MASS-DYEING LINEAR POLYAMIDES USING DYESALTS FROM 1:2 CHROMIUM COMPLEXES OF MONOAZODYES; THE FIBRES OBTAINED THEREFROM CIBA-GEIGY AG (CH) 1983-12-28 EP disclosed
EP-0001786-B1 CRYSTALLINE POLYAMIDE, ITS APPLICATION AND DIAMINES CIBA-GEIGY AG (CH) 1983-01-05 EP disclosed
EP-0010522-B1 TRANSPARENT COPOLYAMIDES, PROCESS FOR THEIR PRODUCTION AND THEIR USE IN THE MANUFACTURE OF MOULDED ARTICLES CIBA-GEIGY AG (CH) 1982-08-11 EP disclosed
EP-0011600-B1 TRANSPARENT COPOLYAMIDES AND THEIR USE IN PRODUCING MOULDED OBJECTS CIBA-GEIGY AG (CH) 1982-04-14 EP disclosed
US-4304590-A WATER TREATMENT CIBA-GEIGY CORPORATION (US) 1981-12-08 US disclosed
US-4275239-A MONOMERS FOR POLYAMIDES CIBA-GEIGY CORPORATION (US) 1981-06-23 US disclosed
US-4263197-A AMINE SALTS OF CHROMIUM COMPLEXES OF MONOAZO DYES CIBA-GEIGY CORPORATION (US) 1981-04-21 US disclosed
US-4258177-A DICYCLOHEXYLDIAMINES, AND AROMATIC DICARBOXYLIC ACIDS CIBA-GEIGY CORPORATION (US) 1981-03-24 US disclosed
US-4255559-A WITH ISOPHTHALIC ACID AND A BIS(4-AMINOCYCLOHEXYL) ALKANE, MOLDING MATERIAL CIBA-GEIGY CORPORATION (US) 1981-03-10 US disclosed
EP-0017611-A1 Method of combating pests and means therefor CIBA-GEIGY AG (CH) 1980-10-15 EP disclosed
US-4225701-A FILAMENTS AND FIBERS CIBA-GEIGY CORPORATION (US) 1980-09-30 US disclosed
US-4210742-A Transparent polyamides from branched chain diamine CIBA-GEIGY CORPORATION (US) 1980-07-01 US disclosed
EP-0011600-A1 Transparent copolyamides and their use in producing moulded objects CIBA-GEIGY AG (CH) 1980-05-28 EP disclosed
EP-0010522-A1 Transparent copolyamides, process for their production and their use in the manufacture of moulded articles CIBA-GEIGY AG (CH) 1980-04-30 EP disclosed
EP-0001786-A1 Crystalline polyamide, its application and diamines CIBA-GEIGY AG (CH) 1979-05-16 EP disclosed
EP-0000331-A1 Method of mass-dyeing linear polyamides using dyesalts from 1:2 chromium complexes of monoazodyes; the fibres obtained therefrom CIBA-GEIGY AG (CH) 1979-01-24 EP disclosed