SCHEMBL10357074

SCHEMBL10357074

O=C(c1ccc(F)cc1)c1ccc(O)cc1O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.68
KMT2A Q03164 3/20 0.68
GAA P10253 2/20 0.68
USP2 O75604 1/20 0.68
KEAP1 Q14145 1/20 0.68
NFE2L2 Q16236 1/20 0.68
ALDH1A1 P00352 4/20 0.63
SMN1; SMN2 Q16637 2/20 0.63
HPGD P15428 2/20 0.63
NPC1 O15118 1/20 0.63
TP53 P04637 1/20 0.63
MAPT P10636 1/20 0.63
LMNA P02545 3/20 0.58
HTT P42858 3/20 0.58
ESR1 P03372 1/20 0.55
ESR2 Q92731 1/20 0.55
CES2 O00748 1/20 0.53
CA12 O43570 2/20 0.52
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10735111 0.90 MEN1 (0.81) MEN1KMT2AGAAUSP2KEAP1
SCHEMBL29054812 0.89 MEN1 (0.58) MEN1KMT2AGAAUSP2KEAP1
SCHEMBL29375096 0.88 MEN1 (0.78) MEN1KMT2AGAAUSP2KEAP1
SCHEMBL93420 0.88 MEN1 (0.78) MEN1KMT2AGAAUSP2KEAP1
SCHEMBL10354488 0.86 MEN1 (0.75) MEN1KMT2AGAAUSP2KEAP1
SCHEMBL13885068 0.85 KMT2A (0.54) MEN1KMT2AGAAUSP2KEAP1
SCHEMBL2128469 0.83 MEN1 (0.76) MEN1KMT2AGAAUSP2KEAP1
SCHEMBL3029820 0.82 KCNMA1 (0.53) MEN1KMT2AGAAUSP2KEAP1
SCHEMBL2989871 0.82 HPGD (0.47) MEN1KMT2AGAAUSP2KEAP1
SCHEMBL16993471 0.82 MEN1 (0.59) MEN1KMT2AGAAUSP2KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116622665-A Method for generating O-glycoside through biocatalysis 湖南师范大学 2023-08-22 CN claimed
CN-116622664-B Method for generating C-glycoside through biocatalysis 湖南师范大学 2026-01-23 CN disclosed
CN-116622665-A Method for generating O-glycoside through biocatalysis 湖南师范大学 2023-08-22 CN disclosed
CN-116622665-A Method for generating O-glycoside through biocatalysis 湖南师范大学 2023-08-22 CN disclosed
CN-116622664-A Method for generating C-glycoside through biocatalysis 湖南师范大学 2023-08-22 CN disclosed
CN-116622664-A Method for generating C-glycoside through biocatalysis 湖南师范大学 2023-08-22 CN disclosed
US-20220362276-A1 Small Molecule Inhibitors of Viral Replication THE TRUSTEES OF PRINCETON UNIVERSITY 2022-11-17 US disclosed
WO-2020231979-A9 SMALL MOLECULE INHIBITORS OF VIRAL REPLICATION THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2021-06-17 WO disclosed
WO-2020231979-A1 SMALL MOLECULE INHIBITORS OF VIRAL REPLICATION THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2020-11-19 WO disclosed
EP-0112587-B1 DERIVATIVES OF 4-(1-(PHENYL)-1-(HYDROXY)-PROP-1-YL)-RESORCINE, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) 1990-09-19 EP disclosed
US-4510338-A TREATMENT OF ACUTE ETHANOLIC INTOXICATION/- RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 1985-04-09 US disclosed
EP-0112587-A2 Derivatives of 4-(1-(phenyl)-1-(hydroxy)-prop-1-yl)-resorcine, process for their preparation and medicines containing these compounds RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) 1984-07-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220362276-A1 Small Molecule Inhibitors of Viral Replication HSPH1, HSP90AB1, HSP90AA1 MEN1 4192/4885KMT2A 3931/4885GAA 733/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.