Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.81 |
| ▸ | USP2 | O75604 | 1/20 | 0.81 |
| ▸ | GAA | P10253 | 1/20 | 0.81 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.81 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.73 |
| ▸ | HPGD | P15428 | 3/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.73 |
| ▸ | NPC1 | O15118 | 1/20 | 0.73 |
| ▸ | TP53 | P04637 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | CES2 | O00748 | 1/20 | 0.64 |
| ▸ | CA12 | O43570 | 4/20 | 0.61 |
| ▸ | CA1 | P00915 | 4/20 | 0.61 |
| ▸ | CA2 | P00918 | 4/20 | 0.61 |
| ▸ | CA7 | P43166 | 4/20 | 0.61 |
| ▸ | CA9 | Q16790 | 4/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29375096 | 0.98 | MEN1 (0.78) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL93420 | 0.98 | MEN1 (0.78) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL10354488 | 0.96 | MEN1 (0.75) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL2128469 | 0.92 | MEN1 (0.76) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL30204017 | 0.90 | MEN1 (0.68) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL30375015 | 0.90 | KMT2A (0.68) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL7679540 | 0.90 | MEN1 (0.68) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL3812381 | 0.90 | MEN1 (0.68) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL10357074 | 0.90 | MEN1 (0.68) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL1101897 | 0.90 | KMT2A (0.68) | MEN1KMT2AUSP2GAAKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4649181-A | Glycidyloxy diketones | CIBA-GEIGY CORPORATION (US) | 1987-03-10 | — | — | US | disclosed |
| EP-0157740-A2 | Glycidyloxydiketones | CIBA-GEIGY AG (CH) | 1985-10-09 | — | — | EP | disclosed |