SCHEMBL10357553

SCHEMBL10357553

Nc1cc(S(=O)(=O)O)cc2c(O)cc(S(=O)(=O)O)cc12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP6 P55212 5/20 0.62
HSD17B10 Q99714 5/20 0.62
ALDH1A1 P00352 5/20 0.62
CYP2C9 P11712 2/20 0.62
CYP2C19 P33261 2/20 0.62
NT5E P21589 4/20 0.59
NSD2 O96028 4/20 0.54
DUSP3 P51452 2/20 0.54
PTPN5 P54829 2/20 0.54
PTPN11 Q06124 2/20 0.54
GAA P10253 3/20 0.51
PLCG1 P19174 1/20 0.51
DNMT1 P26358 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
PRMT1 Q99873 1/20 0.42
MAPT P10636 2/20 0.42
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA9 Q16790 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26612443 0.98 CASP6 (0.61) CASP6HSD17B10ALDH1A1CYP2C9CYP2C19
SCHEMBL5711925 0.89 ALDH1A1 (0.68) CASP6HSD17B10ALDH1A1CYP2C9CYP2C19
SCHEMBL9192954 0.87 CASP6 (0.55) CASP6HSD17B10ALDH1A1CYP2C9CYP2C19
SCHEMBL29401094 0.82 HSD17B10 (0.53) CASP6HSD17B10ALDH1A1CYP2C9CYP2C19
SCHEMBL155753 0.82 HSD17B10 (0.53) CASP6HSD17B10ALDH1A1CYP2C9CYP2C19
Water SCHEMBL3355098 0.80 HSD17B10 (0.51) CASP6HSD17B10ALDH1A1CYP2C9CYP2C19
SCHEMBL7823392 0.80 ALDH1A1 (0.62) CASP6HSD17B10ALDH1A1CYP2C9CYP2C19
Water SCHEMBL29022556 0.79 CASP6 (0.50) CASP6HSD17B10ALDH1A1CYP2C9CYP2C19
SCHEMBL4649751 0.78 CASP6 (0.62) CASP6HSD17B10ALDH1A1CYP2C9CYP2C19
SCHEMBL4881379 0.78 CASP6 (0.57) CASP6HSD17B10ALDH1A1CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230346847-A1 JUVENILE PROTECTIVE FACTORS TO ARREST AND REVERSE AGING IN THE ENTERIC NERVOUS SYSTEM THE JOHNS HOPKINS UNIVERSITY 2023-11-02 US disclosed
CN-106232214-B Composite polyamide membrane post-treated with nitrous acid 陶氏环球技术有限责任公司 2021-01-15 CN disclosed
CN-105848758-B Separation of hydrocarbons from aqueous mixtures using fouling resistant reverse osmosis membranes 陶氏环球技术有限责任公司 2020-01-17 CN disclosed
CN-105848759-B Desalting an aqueous mixture containing nanosized particles using a fouling resistant reverse osmosis membrane 陶氏环球技术有限责任公司 2019-04-02 CN disclosed
CN-105873665-B Composite polyamide membrane post-treated with nitrous acid 陶氏环球技术有限责任公司 2019-01-01 CN disclosed
EP-3142777-B1 COMPOSITE POLYAMIDE MEMBRANE POST TREATED WITH NITROUS ACID DOW GLOBAL TECHNOLOGIES LLC (US) 2018-10-24 EP disclosed
EP-3092057-B1 TREATMENT OF AQUEOUS MIXTURES CONTAINING ANIONIC SURFACTANTS USING FOULING RESISTANT REVERSE OSMOSIS MEMBRANE DOW GLOBAL TECHNOLOGIES LLC (US) 2018-09-19 EP disclosed
EP-3092056-B1 DESALINATION OF AQUEOUS MIXTURE CONTAINING NANO-SIZED PARTICLES USING FOULING RESISTANT REVERSE OSMOSIS MEMBRANE DOW GLOBAL TECHNOLOGIES LLC (US) 2018-08-01 EP disclosed
EP-3077088-B1 METHOD FOR FORMING A COMPOSITE POLYAMIDE MEMBRANE POST TREATED WITH NITRIOUS ACID DOW GLOBAL TECHNOLOGIES LLC (US) 2017-12-27 EP disclosed
US-9808769-B2 Composite polyamide membrane post treated with nitrious acid DOW GLOBAL TECHNOLOGIES LLC (US) 2017-11-07 US disclosed
CN-105848758-A Separation of hydrocarbons from aqueous mixtures using fouling resistant reverse osmosis membranes 陶氏环球技术有限责任公司 2016-08-10 CN disclosed
CN-105848759-A Desalting an aqueous mixture containing nanosized particles using a fouling resistant reverse osmosis membrane 陶氏环球技术有限责任公司 2016-08-10 CN disclosed
WO-2015175256-A1 COMPOSITE POLYAMIDE MEMBRANE POST TREATED WITH NITROUS ACID DOW GLOBAL TECHNOLOGIES LLC (US) 2015-11-19 WO disclosed
EP-0265857-B1 WATER-SOLUBLE MONOAZODYES CONTAINING A UREIDO GROUP AND TWO SULFONYL FIBER-REACTIVE GROUPS, PROCESS FOR THEIR PREPARATION AND THEIR USE HOECHST CELANESE CORPORATION (US) 1990-09-19 EP disclosed
US-4866162-A Fiber-reactive fluoro-triazine containing dyestuff CIBA-GEIGY CORPORATION (US) 1989-09-12 US disclosed
US-4855411-A Water-soluble, monoazo dyes containing a ureido group and two sulfonyl fiber-reactive groups Crall, Hugh C. (US) 1989-08-08 US disclosed
EP-0265857-A1 Water-soluble monoazodyes containing a ureido group and two sulfonyl fiber-reactive groups, process for their preparation and their use HOECHST CELANESE CORPORATION (US) 1988-05-04 EP disclosed
EP-0103156-B1 COPPER COMPLEX OF WATER SOLUBLE DISAZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1986-10-08 EP disclosed
EP-0103156-A2 Copper complex of water soluble disazo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1984-03-21 EP disclosed
US-4252529-A AMINOPHENOL OR AMINONAPHTHOL COMPOUND WITH SUBSTITUTED FIBER-REACTIVE RADICAL HOECHST AKTIENGESELLSCHAFT (DE) 1981-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230346847-A1 JUVENILE PROTECTIVE FACTORS TO ARREST AND REVERSE AGING IN THE ENTERIC NERVOUS SYSTEM FABP2, GAP43, CHAT CASP6 581/4885HSD17B10 3403/4885ALDH1A1 2056/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.