Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.56 |
| ▸ | BCL9 | O00512 | 1/20 | 0.51 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2234364 | 0.89 | MGLL (0.62) | MGLLBCL9CTNNB1MAPTHTR2A | |
| SCHEMBL26976962 | 0.89 | MGLL (0.62) | MGLLBCL9CTNNB1MAPTHTR2A | |
| SCHEMBL21433779 | 0.89 | MGLL (0.62) | MGLLBCL9CTNNB1MAPTHTR2A | |
| SCHEMBL21777065 | 0.89 | MGLL (0.62) | MGLLBCL9CTNNB1MAPTHTR2A | |
| SCHEMBL21433889 | 0.89 | MGLL (0.62) | MGLLBCL9CTNNB1MAPTHTR2A | |
| SCHEMBL10685191 | 0.89 | MGLL (0.62) | MGLLBCL9CTNNB1MAPTHTR2A | |
| SCHEMBL26980348 | 0.89 | MGLL (0.62) | MGLLBCL9CTNNB1MAPTHTR2A | |
| SCHEMBL9846659 | 0.89 | MGLL (0.62) | MGLLBCL9CTNNB1MAPTHTR2A | |
| SCHEMBL21433828 | 0.89 | MGLL (0.62) | MGLLBCL9CTNNB1MAPTHTR2A | |
| SCHEMBL1958366 | 0.87 | MGLL (0.60) | MGLLBCL9CTNNB1MAPTHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0167451-B1 | A NEW PROCESS FOR PREPARING NOVEL N-(ACYLOXY-ALKOXY) CARBONYL DERIVATIVES USEFUL AS BIOREVERSIBLE PRODRUG MOIETIES FOR PRIMARY AND SECONDARY AMINE FUNCTIONS IN DRUGS | MERCK & CO. INC. (US) | 1990-10-03 | — | — | EP | disclosed |