SCHEMBL10357909

SCHEMBL10357909

C=CCOCCOc1ccc(C(=O)Cl)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.49
ALDH1A1 P00352 2/20 0.49
MAPT P10636 5/20 0.44
PKM P14618 1/20 0.44
HTT P42858 1/20 0.43
RAB9A P51151 3/20 0.42
NPC1 O15118 3/20 0.42
POLB P06746 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
PARP10 Q53GL7 1/20 0.41
RARB P10826 1/20 0.41
LMNA P02545 1/20 0.41
CHRNB2 P17787 1/20 0.40
CHRNB4 P30926 1/20 0.40
CHRNA3 P32297 1/20 0.40
CHRNA4 P43681 1/20 0.40
GAA P10253 1/20 0.40
LSS P48449 1/20 0.40
THRA P10827 1/20 0.40
THRB P10828 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10357904 0.96 RARB (0.48) L3MBTL1ALDH1A1MAPTPKMHTT
SCHEMBL5479108 0.92 L3MBTL1 (0.51) L3MBTL1ALDH1A1MAPTHTTRAB9A
SCHEMBL8915810 0.86 ALDH1A1 (0.67) L3MBTL1ALDH1A1MAPTPKMHTT
SCHEMBL711175 0.85 NPC1 (0.54) L3MBTL1ALDH1A1MAPTRAB9ANPC1
SCHEMBL22815873 0.85 MAPT (0.53) L3MBTL1ALDH1A1MAPTPKMRAB9A
Hydrochloric Acid SCHEMBL11131192 0.84 ALDH1A1 (0.65) L3MBTL1ALDH1A1MAPTPKMHTT
SCHEMBL8917659 0.84 ALDH1A1 (0.65) L3MBTL1ALDH1A1MAPTPKMHTT
SCHEMBL8915809 0.84 ALDH1A1 (0.65) L3MBTL1ALDH1A1MAPTPKMHTT
SCHEMBL10262915 0.83 L3MBTL1 (0.60) L3MBTL1ALDH1A1MAPTRAB9ANPC1
SCHEMBL10261920 0.83 L3MBTL1 (0.60) L3MBTL1ALDH1A1MAPTRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-58135837-A None JP disclosed
EP-0219958-B1 FERROELECTRIC LIQUID CRYSTAL ESTER COMPOUND AND LIQUID CRYSTAL COMPOSITION Chisso Corporation (JP) 1990-12-19 EP disclosed
EP-0219958-A2 Ferroelectric liquid crystal ester compound and liquid crystal composition Chisso Corporation (JP) 1987-04-29 EP disclosed
JP-S58135837-A 4-(BETA-ALKYLOXYETHOXY)BENZOIC ACID 4'-ALKYLPHENYL ESTER CHISSO CORP 1983-08-12 JP disclosed