Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ANPEP | P15144 | 2/20 | 0.33 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10531250 | 0.84 | CYP3A4 (0.46) | CYP3A4APPKMT2AMEN1ALDH1A1 | |
| SCHEMBL10358394 | 0.73 | EPHX1 (0.43) | CYP3A4KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL4663260 | 0.71 | CYP3A4 (0.52) | CYP3A4APP | |
| SCHEMBL18214368 | 0.70 | CYP3A4 (0.54) | CYP3A4APPALDH1A1CMA1 | |
| SCHEMBL4666667 | 0.70 | CYP3A4 (0.47) | CYP3A4APPKMT2AMEN1ALDH1A1 | |
| SCHEMBL9016220 | 0.69 | CYP3A4 (0.53) | CYP3A4APPKMT2AMEN1ALDH1A1 | |
| SCHEMBL4663335 | 0.65 | CYP3A4 (0.48) | CYP3A4KMT2AMEN1 | |
| SCHEMBL9736128 | 0.64 | CYP3A4 (0.41) | CYP3A4APP | |
| Dihydrokawain SCHEMBL5672433 | 0.63 | CYP3A4 (1.00) | CYP3A4ALDH1A1CYP2C19SMN1; SMN2 | |
| Dihydrokawain SCHEMBL18214381 | 0.63 | CYP3A4 (1.00) | CYP3A4ALDH1A1CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0247320-B1 | 5-ARYLALKYL-4-ALKOXY-2(5H)-FURANONES, INTERMEDIATES AND PROCESS FOR THEIR PREPARATION AS WELL AS THEIR APPLICATION AS THERAPEUTICALLY ACTIVE INGREDIENTS | SCHWABE WILLMAR GMBH & CO (DE) | 1990-12-27 | — | — | EP | disclosed |
| US-4855320-A | ANTICONVULSANTS, ANTIEPILEPTICS | DR. WILLMAR SCHWABE GMBH & COMPANY (DE) | 1989-08-08 | — | — | US | disclosed |