Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 5/20 | 0.37 |
| ▸ | PLA2G6 | O60733 | 2/20 | 0.37 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9669974 | 0.87 | NAAA (0.40) | CYP3A4APPNAAA | |
| SCHEMBL9734802 | 0.83 | CYP3A4 (0.40) | CYP3A4APP | |
| SCHEMBL9670637 | 0.82 | NAAA (0.43) | NAAA | |
| SCHEMBL9671073 | 0.82 | NAAA (0.43) | NAAA | |
| SCHEMBL8985077 | 0.82 | NAAA (0.43) | NAAA | |
| SCHEMBL9671370 | 0.81 | PTPN1 (0.46) | APP | |
| SCHEMBL9327053 | 0.78 | PTPN1 (0.43) | — | |
| SCHEMBL9670400 | 0.77 | MMP12 (0.45) | NAAA | |
| SCHEMBL9327478 | 0.77 | PTPN1 (0.42) | APPNAAA | |
| SCHEMBL9671026 | 0.75 | NAAA (0.39) | CYP3A4NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134128-A | Immunosuppressive and antiproliferative activity for psoriasis and calcium homeostasis | ALLERGAN, INC. (US) | 1992-07-28 | — | — | US | disclosed |
| EP-0295056-A1 | Anti-inflammatory furanones | ALLERGAN, INC (US) | 1988-12-14 | — | — | EP | disclosed |