Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | UBE2M | P61081 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10358336 | 0.78 | SMN1; SMN2 (0.41) | MAPTSMN1; SMN2TP53LMNANPC1 | |
| SCHEMBL10759361 | 0.78 | DYRK1A (0.39) | DYRK1AMAPTSMN1; SMN2TP53LMNA | |
| SCHEMBL10358298 | 0.69 | DDB1 (0.41) | DYRK1AMAPTSMN1; SMN2TP53IDO1 | |
| SCHEMBL20135675 | 0.68 | NPC1 (0.68) | DYRK1AMAPTSMN1; SMN2TP53LMNA | |
| SCHEMBL29688848 | 0.68 | NPC1 (0.68) | DYRK1AMAPTSMN1; SMN2TP53LMNA | |
| SCHEMBL26567985 | 0.67 | MAPT (0.43) | DYRK1AMAPTSMN1; SMN2TP53LMNA | |
| SCHEMBL13082023 | 0.67 | NPC1 (0.49) | DYRK1AMAPTSMN1; SMN2TP53LMNA | |
| SCHEMBL23010591 | 0.64 | UBE2M (0.50) | MAPTSMN1; SMN2TP53LMNANPC1 | |
| SCHEMBL26049456 | 0.63 | DDB1 (0.43) | — | |
| SCHEMBL92781 | 0.63 | SMN1; SMN2 (0.61) | DYRK1AMAPTSMN1; SMN2TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161222-B1 | HETEROCYCLIC MERCAPTOCARBOXYLIC-ACID AMIDES, IMIDES AND NITRILES AS CORROSION INHIBITING AGENTS | CIBA-GEIGY AG (CH) | 1990-10-10 | — | — | EP | disclosed |
| US-4719036-A | PAINTS; METAL WORKING | CIBA-GEIGY CORPORATION (US) | 1988-01-12 | — | — | US | disclosed |
| EP-0161222-A2 | Heterocyclic mercaptocarboxylic-acid amides, imides and nitriles as corrosion inhibiting agents | CIBA-GEIGY AG (CH) | 1985-11-13 | — | — | EP | disclosed |