Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 10/20 | 0.40 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 3/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10358607 | 0.82 | MEN1 (0.47) | SMN1; SMN2CRBNMAPTGAANPC1 | |
| SCHEMBL10761387 | 0.78 | MAPT (0.42) | SMN1; SMN2CA1CA2CA4CRBN | |
| SCHEMBL10358301 | 0.78 | DYRK1A (0.39) | SMN1; SMN2MAPTGAANPC1RAB9A | |
| SCHEMBL22201585 | 0.70 | SMN1; SMN2 (0.54) | SMN1; SMN2CA1CA2CA4MAPT | |
| SCHEMBL10358334 | 0.69 | KEAP1 (0.50) | SMN1; SMN2CA1CA2CA4CRBN | |
| SCHEMBL3851706 | 0.67 | SMN1; SMN2 (0.43) | SMN1; SMN2CA1CA2CA4CRBN | |
| SCHEMBL8304295 | 0.67 | SMN1; SMN2 (0.43) | SMN1; SMN2CA1CA2CA4CRBN | |
| SCHEMBL31703846 | 0.63 | SMN1; SMN2 (0.49) | SMN1; SMN2CA1CA2CA4MAPT | |
| SCHEMBL334946 | 0.63 | RAB9A (0.66) | SMN1; SMN2CA1CA2CA4MAPT | |
| SCHEMBL31730151 | 0.62 | CRBN (0.58) | SMN1; SMN2CA1CA2CA4CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161222-B1 | HETEROCYCLIC MERCAPTOCARBOXYLIC-ACID AMIDES, IMIDES AND NITRILES AS CORROSION INHIBITING AGENTS | CIBA-GEIGY AG (CH) | 1990-10-10 | — | — | EP | disclosed |
| US-4719036-A | PAINTS; METAL WORKING | CIBA-GEIGY CORPORATION (US) | 1988-01-12 | — | — | US | disclosed |
| EP-0161222-A2 | Heterocyclic mercaptocarboxylic-acid amides, imides and nitriles as corrosion inhibiting agents | CIBA-GEIGY AG (CH) | 1985-11-13 | — | — | EP | disclosed |