Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 4/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HTT | P42858 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10762468 | 0.79 | LMNA (0.33) | SMN1; SMN2ALDH1A1HTTMAPTLMNA | |
| SCHEMBL10358379 | 0.73 | GAA (0.40) | DDB1CRBNSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL10358298 | 0.71 | DDB1 (0.41) | DDB1CRBNSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL10358255 | 0.71 | DDB1 (0.36) | DDB1CRBNSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL10358343 | 0.71 | — | — | |
| SCHEMBL10358606 | 0.70 | HSD17B10 (0.57) | DDB1CRBNSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL10358340 | 0.69 | SMN1; SMN2 (0.30) | SMN1; SMN2 | |
| SCHEMBL10358334 | 0.69 | KEAP1 (0.50) | DDB1CRBNSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL10761754 | 0.69 | LMNA (0.33) | SMN1; SMN2LMNAPOLB | |
| SCHEMBL9306224 | 0.66 | GAA (0.32) | RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161222-B1 | HETEROCYCLIC MERCAPTOCARBOXYLIC-ACID AMIDES, IMIDES AND NITRILES AS CORROSION INHIBITING AGENTS | CIBA-GEIGY AG (CH) | 1990-10-10 | — | — | EP | disclosed |
| US-4719036-A | PAINTS; METAL WORKING | CIBA-GEIGY CORPORATION (US) | 1988-01-12 | — | — | US | disclosed |
| EP-0161222-A2 | Heterocyclic mercaptocarboxylic-acid amides, imides and nitriles as corrosion inhibiting agents | CIBA-GEIGY AG (CH) | 1985-11-13 | — | — | EP | disclosed |