SCHEMBL10358945

SCHEMBL10358945

CCN(CC)CCc1cc(Cl)ccc1Oc1ccc(Cl)cc1CCN(CC)CC

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 10/20 0.45
SLC6A2 P23975 9/20 0.45
SLC6A3 Q01959 6/20 0.43
HTR2A P28223 1/20 0.43
KCNH2 Q12809 1/20 0.43
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.43
LMNA P02545 1/20 0.43
MAPK1 P28482 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28299433 0.84 SLC6A2 (0.63) SLC6A4SLC6A2SLC6A3HTR2AKCNH2
SCHEMBL10358948 0.81 ALDH1A1 (0.49) SLC6A4SLC6A2SLC6A3HTR2AKCNH2
SCHEMBL16098372 0.78 HIF1A (0.53) SLC6A2SLC6A3KCNH2KDM4EMEN1
SCHEMBL16098781 0.78 KCNH2 (0.37) KCNH2KDM4ELMNA
SCHEMBL6297379 0.77 SLC6A4 (0.45) SLC6A4SLC6A2SLC6A3HTR2AKCNH2
SCHEMBL3958609 0.75 DRD2 (0.49) SLC6A4SLC6A2SLC6A3HTR2A
SCHEMBL14578206 0.73 KDM4E (0.51) HTR2AKDM4EMEN1LMNAMAPK1
Hydrochloric Acid SCHEMBL11840122 0.73 ATM (0.47) KCNH2MEN1LMNAKMT2A
SCHEMBL7061118 0.71 HTR2A (0.43) SLC6A2SLC6A3HTR2AKCNH2KDM4E
SCHEMBL8160947 0.71 SLC6A2 (0.51) SLC6A4SLC6A2SLC6A3KCNH2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0109563-B1 METHOD OF INCREASING BIOMASS IN PLANTS US AGRICULTURE (US) 1990-10-10 EP disclosed
US-4797153-A PLANT GROWTH REGULATORS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1989-01-10 US disclosed
WO-1984001489-A1 METHOD OF INCREASING BIOMASS IN PLANTS US AGRICULTURE (US) 1984-04-26 WO disclosed