Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2137755 | 0.81 | LMNA (0.55) | ALDH1A1CYP2D6MAPTGAAMEN1 | |
| SCHEMBL9820882 | 0.79 | MEN1 (0.54) | MAPTGAAMEN1KMT2ALMNA | |
| SCHEMBL22897750 | 0.79 | ALDH1A1 (0.50) | ALDH1A1CYP2D6MAPTKDM4EGAA | |
| SCHEMBL10437967 | 0.77 | ATM (0.56) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL29974945 | 0.77 | ALDH1A1 (0.49) | ALDH1A1CYP2D6MAPTKDM4EGAA | |
| SCHEMBL23579273 | 0.75 | MEN1 (0.57) | ALDH1A1MAPTKDM4EGAAMEN1 | |
| SCHEMBL18797039 | 0.75 | MEN1 (0.53) | ALDH1A1CYP2D6MAPTGAAMEN1 | |
| SCHEMBL18797038 | 0.75 | MEN1 (0.53) | ALDH1A1CYP2D6MAPTGAAMEN1 | |
| SCHEMBL10185112 | 0.73 | MAPT (0.49) | ALDH1A1CYP2D6MAPTKDM4EGAA | |
| SCHEMBL4604698 | 0.73 | MAPT (0.66) | ALDH1A1CYP2D6MAPTGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0206435-B1 | 2,4-DIHALO-5-SUBSTITUTED PHENYLHYDRAZINES AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-11-14 | — | — | EP | claimed |
| EP-0206435-A2 | 2,4-Dihalo-5-substituted phenylhydrazines and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-12-30 | — | — | EP | claimed |