⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10359162 | 1.00 | — | — | |
| SCHEMBL10358504 | 0.78 | — | — | |
| SCHEMBL10358502 | 0.78 | — | — | |
| SCHEMBL10358240 | 0.78 | — | — | |
| SCHEMBL10358241 | 0.78 | — | — | |
| SCHEMBL641523 | 0.78 | — | — | |
| SCHEMBL21253086 | 0.73 | GLO1 (0.32) | — | |
| SCHEMBL502559 | 0.72 | ALDH1A1 (0.43) | — | |
| SCHEMBL18918462 | 0.72 | — | — | |
| SCHEMBL27734167 | 0.72 | CA12 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0184692-B1 | METHOD OF PREPARATION OF O-SILYLATED KETENE ACETALS AND ENOL ETHERS | UNION CARBIDE CORPORATION (US) | 1990-12-27 | — | — | EP | disclosed |
| US-4780554-A | O-silylated ketene acetals and enol ethers and method of preparation | UNION CARBIDE CORPORATION (US) | 1988-10-25 | — | — | US | disclosed |
| EP-0184692-A1 | Method of preparation of o-silylated ketene acetals and enol ethers | UNION CARBIDE CORPORATION (US) | 1986-06-18 | — | — | EP | disclosed |