Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 6/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.56 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | RAD52 | P43351 | 1/20 | 0.52 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Norfloxacin Succinil SCHEMBL29362122 | 0.88 | HSD17B10 (0.83) | HSD17B10MEN1KMT2AHIF1ADRD3 | |
| Norfloxacin Succinil SCHEMBL10358912 | 0.88 | HSD17B10 (0.83) | HSD17B10MEN1KMT2AHIF1ADRD3 | |
| SCHEMBL7824016 | 0.86 | DRD3 (0.63) | HSD17B10MEN1KMT2AHIF1ADRD3 | |
| SCHEMBL2849523 | 0.86 | DRD3 (0.76) | HSD17B10MEN1KMT2ADRD3KDM4E | |
| SCHEMBL2858133 | 0.84 | KDM4E (0.77) | HSD17B10MEN1KMT2AHIF1ADRD3 | |
| SCHEMBL10810567 | 0.84 | KDM4E (0.58) | HSD17B10MEN1KMT2AHIF1AKDM4E | |
| SCHEMBL10919032 | 0.81 | KDM4E (0.61) | HSD17B10MEN1KMT2AHIF1AKDM4E | |
| Glutamic Acid SCHEMBL11011088 | 0.80 | KDM4E (0.62) | HSD17B10MEN1KMT2AHIF1ADRD3 | |
| SCHEMBL11113316 | 0.79 | KDM4E (0.57) | HSD17B10MEN1KMT2AHIF1AKDM4E | |
| SCHEMBL9667763 | 0.79 | KDM4E (0.55) | HSD17B10MEN1KMT2AHIF1ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155006-B1 | COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FARMADES S.p.A. (IT) | 1990-10-24 | — | — | EP | claimed |