Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25407017 | 0.85 | CDK2 (0.32) | — | |
| SCHEMBL29142120 | 0.78 | DAO (0.36) | GABRA1GABRB2 | |
| SCHEMBL30681830 | 0.73 | BID (0.43) | MMP2KDM4EMAPT | |
| SCHEMBL23197979 | 0.71 | APOBEC3G (0.48) | PDK2APOBEC3GMMP2MMP3MMP9 | |
| SCHEMBL9669892 | 0.71 | PTGER4 (0.44) | MMP2MMP9KDM4ELMNATP53 | |
| SCHEMBL194707 | 0.69 | ADORA2A (0.41) | KDM4EMAPTTSHR | |
| SCHEMBL2266147 | 0.69 | CES1 (0.38) | LMNATSHR | |
| SCHEMBL30681832 | 0.69 | HDAC4 (0.42) | LMNAMAPT | |
| SCHEMBL7584603 | 0.69 | PDCD1 (0.43) | PDK2APOBEC3GMMP2MMP3MMP9 | |
| SCHEMBL14661712 | 0.68 | KEAP1 (0.47) | PDK2KDM4ELMNAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213091-B1 | USE OF COMPOUNDS FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF CATARACT | Testa, Michele (IT) | 1990-10-24 | — | — | EP | disclosed |