SCHEMBL25407017

SCHEMBL25407017

O=C1N=Nc2cccc(CCO)c21

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CDK2 P24941 2/20 0.32
KDR P35968 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10359472 0.85 PDK2 (0.33)
SCHEMBL2313485 0.69 MAOA (0.48)
SCHEMBL2311538 0.68 MAOA (0.50)
SCHEMBL30900308 0.68 PDCD1 (0.34) CDK2KDR
SCHEMBL194707 0.67 ADORA2A (0.41)
SCHEMBL2266147 0.67 CES1 (0.38)
SCHEMBL4750390 0.67 ALDH1A1 (0.46)
SCHEMBL14661712 0.66 KEAP1 (0.47) KDR
SCHEMBL2316204 0.66 MEN1 (0.54)
SCHEMBL1424202 0.64 KDM4E (0.45) CDK2KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023138612-A1 HETEROCYCLIC COMPOUNDS USEFUL AS HPK1 INHIBITORS SILEXON AI TECHNOLOGY CO., LTD. (CN) 2023-07-27 WO disclosed