Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | CDC25C | P30307 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 5/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 3/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.34 |
| ▸ | PPARD | Q03181 | 3/20 | 0.34 |
| ▸ | PPARA | Q07869 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | FABP4 | P15090 | 2/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10915846 | 1.00 | CDC25A (0.36) | CDC25ACDC25BCDC25CALOX5PPARG | |
| SCHEMBL10359294 | 1.00 | CDC25A (0.36) | CDC25ACDC25BCDC25CALOX5PPARG | |
| SCHEMBL10359296 | 1.00 | CDC25A (0.36) | CDC25ACDC25BCDC25CALOX5PPARG | |
| SCHEMBL10359569 | 1.00 | CDC25A (0.36) | CDC25ACDC25BCDC25CALOX5PPARG | |
| SCHEMBL10359741 | 0.88 | ALOX5 (0.39) | CDC25ACDC25BCDC25CALOX5PPARG | |
| SCHEMBL10359819 | 0.88 | ALOX5 (0.39) | CDC25ACDC25BCDC25CALOX5PPARG | |
| SCHEMBL10359818 | 0.88 | ALOX5 (0.39) | CDC25ACDC25BCDC25CALOX5PPARG | |
| SCHEMBL10359722 | 0.87 | ALOX5 (0.47) | ALOX5PPARGTERTPTPN1PPARD | |
| SCHEMBL10359720 | 0.87 | ALOX5 (0.47) | ALOX5PPARGTERTPTPN1PPARD | |
| SCHEMBL10767238 | 0.77 | PRKCA (0.45) | PPARGPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213547-B1 | CYCLOHEXANEALKANOIC ACIDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-12-27 | — | — | EP | disclosed |
| US-4622422-A | FOR TREATMENT OF BRONCHIAL ASTHMA | MERRELL DOW PHARMACEUTICALS INC. (US) | 1986-11-11 | — | — | US | disclosed |