Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.55 |
| ▸ | OGT | O15294 | 1/20 | 0.53 |
| ▸ | NOS1 | P29475 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10338403 | 0.84 | PDE3B (0.61) | SYKOGTNOS1ALDH1A1POLB | |
| SCHEMBL16208493 | 0.82 | KIF11 (0.60) | SYK | |
| SCHEMBL24897475 | 0.81 | SYK (0.50) | SYKOGTNOS1ALDH1A1LMNA | |
| SCHEMBL10437432 | 0.80 | SYK (0.49) | SYKOGTNOS1ALDH1A1LMNA | |
| SCHEMBL10437477 | 0.79 | SYK (0.48) | SYKOGTNOS1CREBBPJAK1 | |
| SCHEMBL9381947 | 0.79 | CDC7 (0.61) | SYKOGTNOS1LMNAGRIN2D | |
| SCHEMBL30494280 | 0.79 | PDE3B (0.54) | SYKOGTNOS1ALPLALPI | |
| SCHEMBL26463639 | 0.79 | PDE3B (0.54) | SYKOGTNOS1ALPLALPI | |
| SCHEMBL8311380 | 0.78 | NOS1 (0.61) | SYKOGTNOS1ALDH1A1LMNA | |
| SCHEMBL24897509 | 0.78 | PSMB8 (0.74) | ALDH1A1ALPLALPIALPGCREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2083376-A | — | — | None | — | — | JP | disclosed |
| EP-0360566-A2 | Lipoxygenase/cyclooxygenase inhibiting benzoxazolones | PFIZER INC. (US) | 1990-03-28 | — | — | EP | disclosed |
| JP-H0283376-A | BENZOXAZOLONE DERIVATIVE AND ANTIALLERGIC OR ANTI-INFLAMMATORY COMPOSITION | PFIZER PHARMACEUT CO LTD | 1990-03-23 | — | — | JP | disclosed |