Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A12 | P48065 | 5/20 | 0.39 |
| ▸ | SLC6A11 | P48066 | 5/20 | 0.39 |
| ▸ | SLC6A13 | Q9NSD5 | 5/20 | 0.39 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10359716 | 1.00 | SLC6A12 (0.39) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL10359376 | 1.00 | SLC6A12 (0.39) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL10359377 | 1.00 | SLC6A12 (0.39) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL6076661 | 0.74 | SLC6A12 (0.44) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL6435442 | 0.74 | GBA1 (0.32) | — | |
| SCHEMBL9278180 | 0.72 | SLC6A12 (0.57) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL6436262 | 0.72 | — | — | |
| SCHEMBL17281763 | 0.71 | SLC6A12 (0.41) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL21510329 | 0.69 | SLC6A12 (0.40) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL19190079 | 0.69 | SLC6A12 (0.40) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213547-B1 | CYCLOHEXANEALKANOIC ACIDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-12-27 | — | — | EP | disclosed |
| EP-0213547-A1 | Cyclohexanealkanoic acids | MERRELL DOW PHARMACEUTICALS INC. (US) | 1987-03-11 | — | — | EP | disclosed |
| US-4622422-A | FOR TREATMENT OF BRONCHIAL ASTHMA | MERRELL DOW PHARMACEUTICALS INC. (US) | 1986-11-11 | — | — | US | disclosed |