Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A12 | P48065 | 5/20 | 0.40 |
| ▸ | SLC6A11 | P48066 | 5/20 | 0.40 |
| ▸ | SLC6A13 | Q9NSD5 | 5/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19190079 | 1.00 | SLC6A12 (0.40) | SLC6A12SLC6A11SLC6A13HSD11B1AKR1C4 | |
| SCHEMBL11556130 | 0.81 | SLC6A12 (0.35) | SLC6A12SLC6A11SLC6A13AKR1C4AKR1C3 | |
| SCHEMBL18088605 | 0.79 | CA1 (0.38) | SLC6A12SLC6A11SLC6A13HSD11B1AKR1C4 | |
| SCHEMBL18853784 | 0.78 | AKR1C4 (0.37) | SLC6A12SLC6A11SLC6A13AKR1C4AKR1C3 | |
| SCHEMBL669993 | 0.77 | AKR1C4 (0.52) | SLC6A12SLC6A11SLC6A13AKR1C4AKR1C3 | |
| SCHEMBL18853787 | 0.77 | AKR1C4 (0.52) | SLC6A12SLC6A11SLC6A13AKR1C4AKR1C3 | |
| SCHEMBL30180824 | 0.77 | AKR1C4 (0.52) | SLC6A12SLC6A11SLC6A13AKR1C4AKR1C3 | |
| SCHEMBL18853799 | 0.77 | AKR1C4 (0.52) | SLC6A12SLC6A11SLC6A13AKR1C4AKR1C3 | |
| SCHEMBL6727788 | 0.77 | AKR1C4 (0.52) | SLC6A12SLC6A11SLC6A13AKR1C4AKR1C3 | |
| SCHEMBL29517213 | 0.77 | AKR1C4 (0.52) | SLC6A12SLC6A11SLC6A13AKR1C4AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2536724-B2 | PROCESS FOR PREPARING ENTECAVIR AND ITS INTERMEDIATES | SCINOPHARM TAIWAN LTD (TW) | 2019-10-23 | — | — | EP | disclosed |