Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7385780 | 0.81 | ALDH1A1 (0.67) | ALDH1A1TSHRHTTCYP1A2KMT2A | |
| SCHEMBL6944126 | 0.81 | ALDH1A1 (0.67) | ALDH1A1TSHRHTTCYP1A2KMT2A | |
| SCHEMBL4362449 | 0.80 | ALDH1A1 (0.33) | ALDH1A1TSHRHSP90AA1HSP90AB1 | |
| SCHEMBL29336758 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TSHRHTTCYP1A2KMT2A | |
| SCHEMBL19419845 | 0.79 | CYP1A2 (0.47) | ALDH1A1TSHRHTTCYP1A2KMT2A | |
| SCHEMBL9888403 | 0.79 | SMN1; SMN2 (0.48) | ALDH1A1TSHRHTTSMN1; SMN2CYP2C19 | |
| SCHEMBL5683703 | 0.77 | ALDH1A1 (0.77) | ALDH1A1TSHRHTTCYP1A2KMT2A | |
| SCHEMBL28831712 | 0.76 | ALDH1A1 (0.42) | ALDH1A1TSHRHTTHSP90AA1HSP90AB1 | |
| SCHEMBL27495429 | 0.76 | HTT (0.43) | ALDH1A1TSHRHTTCYP1A2KMT2A | |
| SCHEMBL2240196 | 0.75 | ALDH1A1 (0.46) | ALDH1A1TSHRHTTCYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8377856-B2 | Extended drain diesel lubricant formulations | AFTON CHEMICAL CORPORATION (US) | 2013-02-19 | — | — | US | claimed |
| US-20110003722-A1 | EXTENDED DRAIN DIESEL LUBRICANT FORMULATIONS | AFTON CHEMICAL CORPORATION (US) | 2011-01-06 | — | — | US | claimed |
| US-20100292112-A1 | EXTENDED DRAIN DIESEL LUBRICANT FORMULATIONS | AFTON CHEMICAL CORPORATION (US) | 2010-11-18 | — | — | US | claimed |
| US-20100292112-A1 | EXTENDED DRAIN DIESEL LUBRICANT FORMULATIONS | AFTON CHEMICAL CORPORATION (US) | 2010-11-18 | — | — | US | disclosed |