Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 12/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 11/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 10/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 10/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 10/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8837045 | 0.85 | SIGMAR1 (0.50) | SMN1; SMN2CHRM3CHRM4CHRM2CHRM5 | |
| SCHEMBL19419845 | 0.83 | CYP1A2 (0.47) | SMN1; SMN2CHRM3CHRM4CHRM2CHRM5 | |
| SCHEMBL1974668 | 0.83 | KIF11 (0.48) | SMN1; SMN2CYP2D6KCNH2ALDH1A1TSHR | |
| SCHEMBL16685240 | 0.82 | ESR1 (0.39) | LMNAALDH1A1TSHRBCL2 | |
| SCHEMBL27495429 | 0.80 | HTT (0.43) | SMN1; SMN2LMNAALDH1A1TSHRKDM4E | |
| SCHEMBL28831712 | 0.80 | ALDH1A1 (0.42) | SMN1; SMN2LMNAALDH1A1TSHRKDM4E | |
| SCHEMBL560935 | 0.79 | SMN1; SMN2 (0.61) | SMN1; SMN2CHRM3CHRM4CHRM2CHRM5 | |
| SCHEMBL1035978 | 0.79 | ALDH1A1 (0.53) | SMN1; SMN2LMNAALDH1A1TSHRKDM4E | |
| SCHEMBL1985443 | 0.78 | ALDH1A1 (0.57) | SMN1; SMN2CHRM3CHRM4CHRM2CHRM5 | |
| SCHEMBL30778224 | 0.78 | ALOX5 (0.44) | SMN1; SMN2ALDH1A1TSHRCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140306153-A1 | LITHIUM-POROUS METAL OXIDE COMPOSITIONS AND LITHIUM REAGENT-POROUS METAL COMPOSITIONS | SIGNA CHEMISTRY, INC. (US) | 2014-10-16 | — | — | US | disclosed |
| US-20140306153-A1 | LITHIUM-POROUS METAL OXIDE COMPOSITIONS AND LITHIUM REAGENT-POROUS METAL COMPOSITIONS | SIGNA CHEMISTRY, INC. (US) | 2014-10-16 | — | — | US | disclosed |
| US-20120235084-A1 | LITHIUM-POROUS METAL OXIDE COMPOSITIONS AND LITHIUM REAGENT-POROUS METAL COMPOSITIONS | SIGNA CHEMISTRY, INC. (US) | 2012-09-20 | — | — | US | disclosed |
| US-20120235084-A1 | LITHIUM-POROUS METAL OXIDE COMPOSITIONS AND LITHIUM REAGENT-POROUS METAL COMPOSITIONS | SIGNA CHEMISTRY, INC. (US) | 2012-09-20 | — | — | US | disclosed |
| US-8197707-B2 | Lithium-porous metal oxide compositions and lithium reagent-porous metal compositions | SIGNA CHEMISTRY LLC (US) | 2012-06-12 | — | — | US | disclosed |
| US-8197707-B2 | Lithium-porous metal oxide compositions and lithium reagent-porous metal compositions | SIGNA CHEMISTRY LLC (US) | 2012-06-12 | — | — | US | disclosed |
| US-8197707-B2 | Lithium-porous metal oxide compositions and lithium reagent-porous metal compositions | SIGNA CHEMISTRY LLC (US) | 2012-06-12 | — | — | US | disclosed |
| US-20080111104-A1 | mixing liquid lithium metal with a porous metal oxide in an inert atmosphere under exothermic conditions sufficient to absorb the liquid lithium metal into the porous metal oxide pores, reacting lithium-metal oxide with a alkyl halide to form alkyllithium-metal oxide reagent used in various reactions | SIGNA CHEMISTRY, LLC (US) | 2008-05-15 | — | — | US | disclosed |
| US-20080111104-A1 | mixing liquid lithium metal with a porous metal oxide in an inert atmosphere under exothermic conditions sufficient to absorb the liquid lithium metal into the porous metal oxide pores, reacting lithium-metal oxide with a alkyl halide to form alkyllithium-metal oxide reagent used in various reactions | SIGNA CHEMISTRY, LLC (US) | 2008-05-15 | — | — | US | disclosed |
| WO-2008031101-A2 | LITHIUM-POROUS METAL OXIDE COMPOSITIONS AND LITHIUM REAGENT-POROUS METAL COMPOSITIONS | SIGNA CHEMISTRY, LLC (US) | 2008-03-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140306153-A1 | LITHIUM-POROUS METAL OXIDE COMPOSITIONS AND LITHIUM REAGENT-POROUS METAL COMPOSITIONS | NR1I2, SLCO2B1, NR1I3 | SMN1; SMN2 4859/4885CHRM3 2200/4885CHRM4 3223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.