Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RPA1 | P27694 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10360365 | 0.89 | MAPT (0.44) | MAPTSMN1; SMN2ALDH1A1KDM4ERPA1 | |
| SCHEMBL10360682 | 0.86 | MAPT (0.43) | MAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL10360673 | 0.86 | MEN1 (0.44) | MAPTSMN1; SMN2ALDH1A1KDM4ERPA1 | |
| SCHEMBL10361334 | 0.86 | TSHR (0.44) | MAPTSMN1; SMN2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL10361312 | 0.86 | MAPT (0.56) | MAPTSMN1; SMN2ALDH1A1KDM4EKMT2A | |
| SCHEMBL10361364 | 0.85 | MAPT (0.42) | MAPTSMN1; SMN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL10360706 | 0.85 | MAPT (0.43) | MAPTSMN1; SMN2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL10361120 | 0.84 | HPGD (0.39) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL10361341 | 0.82 | HPGD (0.39) | MAPTSMN1; SMN2ALDH1A1KDM4EKMT2A | |
| SCHEMBL10360302 | 0.82 | NOTUM (0.43) | MAPTALDH1A1PTGDR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4931083-A | Plant growth regulating triazoles | ELI LILLY AND COMPANY (US) | 1990-06-05 | — | — | US | disclosed |
| EP-0227284-A1 | Plant Growth regulating triazoles | ELI LILLY AND COMPANY (US) | 1987-07-01 | — | — | EP | disclosed |