Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 2/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.40 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.40 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10361148 | 0.90 | NOTUM (0.44) | NOTUMPOLBRXRAGRIN1GRIN2B | |
| SCHEMBL10360343 | 0.89 | HSD17B10 (0.45) | NOTUMPOLBRXRAGRIN1GRIN2B | |
| SCHEMBL10360322 | 0.88 | RXRA (0.40) | NOTUMPOLBRXRAGRIN1GRIN2B | |
| SCHEMBL10361130 | 0.88 | KCNJ6 (0.40) | NOTUMPOLBRXRAGRIN1GRIN2B | |
| SCHEMBL10360325 | 0.88 | RXRA (0.40) | NOTUMPOLBRXRAGRIN1GRIN2B | |
| SCHEMBL10360316 | 0.87 | ALDH1A1 (0.43) | NOTUMPOLBRXRAGRIN1GRIN2B | |
| SCHEMBL10360378 | 0.86 | PPARD (0.44) | ALDH1A1PTGDR2MAPT | |
| SCHEMBL10361173 | 0.85 | ACACB (0.45) | NOTUMRXRAGRIN1GRIN2BKMT2A | |
| SCHEMBL10361364 | 0.85 | MAPT (0.42) | NOTUMRXRAGRIN1GRIN2BALDH1A1 | |
| SCHEMBL10360682 | 0.83 | MAPT (0.43) | NOTUMPOLBALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4931083-A | Plant growth regulating triazoles | ELI LILLY AND COMPANY (US) | 1990-06-05 | — | — | US | claimed |
| US-4931083-A | Plant growth regulating triazoles | ELI LILLY AND COMPANY (US) | 1990-06-05 | — | — | US | disclosed |
| EP-0227284-A1 | Plant Growth regulating triazoles | ELI LILLY AND COMPANY (US) | 1987-07-01 | — | — | EP | disclosed |