Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | OGG1 | O15527 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10361134 | 0.89 | MAPT (0.45) | MAPTTSHRHTR2APKMPOLB | |
| SCHEMBL10361078 | 0.88 | PKM (0.40) | MAPTTSHRPKMPOLBALDH1A1 | |
| SCHEMBL10360673 | 0.88 | MEN1 (0.44) | MAPTPOLBALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL10360745 | 0.87 | TSHR (0.40) | MAPTTSHRHTR2AHTR2CHTR2B | |
| SCHEMBL10360305 | 0.87 | KMT2A (0.45) | MAPTTSHRPKMPOLBALDH1A1 | |
| SCHEMBL10361312 | 0.87 | MAPT (0.56) | MAPTPKMPOLBALDH1A1KDM4E | |
| SCHEMBL10360437 | 0.86 | MAPT (0.42) | MAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL10361364 | 0.86 | MAPT (0.42) | MAPTALDH1A1KDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL10361140 | 0.86 | TSHR (0.45) | MAPTTSHRPKMPOLBALDH1A1 | |
| SCHEMBL10360696 | 0.86 | MAPT (0.43) | MAPTTSHRHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4931083-A | Plant growth regulating triazoles | ELI LILLY AND COMPANY (US) | 1990-06-05 | — | — | US | disclosed |
| EP-0227284-A1 | Plant Growth regulating triazoles | ELI LILLY AND COMPANY (US) | 1987-07-01 | — | — | EP | disclosed |