Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KCNN4 | O15554 | 9/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.35 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10360494 | 0.86 | MAPT (0.38) | MAPTKMT2AKCNN4HTTCHRM3 | |
| SCHEMBL10360491 | 0.82 | MAPT (0.43) | MAPTKMT2AKCNN4HTTCHRM3 | |
| SCHEMBL4525774 | 0.81 | CYP2B6 (0.47) | MAPTKMT2AKCNN4HTTCHRM3 | |
| SCHEMBL9273398 | 0.77 | KMT2A (0.46) | MAPTKMT2ACHRM3CHRM2POLB | |
| Cadaverine Tartrate SCHEMBL4521162 | 0.74 | CYP2B6 (0.40) | MAPTKMT2AKCNN4CHRM3KIF11 | |
| SCHEMBL830791 | 0.71 | MAPT (0.60) | MAPTKMT2AKCNN4HTTCHRM3 | |
| SCHEMBL7413438 | 0.68 | MAPT (0.40) | MAPTKMT2AKCNN4HTTCHRM3 | |
| SCHEMBL812971 | 0.66 | KCNN4 (0.76) | MAPTKMT2AKCNN4HTTCYP1A2 | |
| SCHEMBL8717591 | 0.66 | MAPT (0.54) | MAPTKMT2AKCNN4HTTCHRM3 | |
| SCHEMBL14396643 | 0.66 | CYP2B6 (0.45) | MAPTKMT2AKCNN4CHRM2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178947-B1 | 1-[(Aminoalkyl and aminoalkylamino)carbonyl and thiocarbonyl]-alpha,alpha-diarylpyrrolidine, piperidine and homopiperidineacetamides and acetonitriles | A.H. ROBINS COMPANY, INCORPORATED (US) | 1990-09-26 | — | — | EP | disclosed |