Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 15/20 | 0.76 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.56 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18782553 | 0.87 | KCNN4 (0.72) | KCNN4MAPTKMT2AKCNE1KCNQ1 | |
| Senicapoc SCHEMBL1443805 | 0.87 | KCNN4 (1.00) | KCNN4MAPTKMT2AKCNE1KCNQ1 | |
| SCHEMBL2337394 | 0.87 | KCNN4 (1.00) | KCNN4MAPTKMT2AKCNE1KCNQ1 | |
| SCHEMBL6167052 | 0.82 | KCNN4 (0.61) | KCNN4MAPTKMT2AKCNE1KCNQ1 | |
| SCHEMBL17592012 | 0.82 | KCNN4 (0.56) | KCNN4MAPTKMT2AKCNE1KCNQ1 | |
| SCHEMBL13950934 | 0.82 | KCNN4 (1.00) | KCNN4MAPTKMT2AKCNE1KCNQ1 | |
| SCHEMBL28316877 | 0.81 | KCNN4 (0.59) | KCNN4KMT2AKCNE1KCNQ1TSHR | |
| SCHEMBL14437486 | 0.81 | KCNN4 (0.65) | KCNN4MAPTKMT2AKCNE1KCNQ1 | |
| SCHEMBL14437487 | 0.81 | KCNN4 (1.00) | KCNN4MAPTKMT2AKCNE1KCNQ1 | |
| SCHEMBL12811863 | 0.81 | KCNN4 (0.86) | KCNN4KCNE1KCNQ1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119246718-A | Chiral analysis method of semaglutin series intermediates | 杭州澳赛诺医药技术有限公司 | 2025-01-03 | — | — | CN | claimed |
| CN-115943138-A | Compositions comprising GARDOS channel antagonists and uses thereof | 阿迪玛生物有限责任公司 | 2023-04-07 | — | — | CN | claimed |
| US-20110124735-A1 | CARBONYLAMINO DERIVATIVES USEFUL FOR THE TREATMENT OF CERTAIN INFLAMMATORY DISORDERS | NEURO SEARCH A/S (DK) | 2011-05-26 | — | — | US | claimed |
| EP-2192896-A1 | CARBONYLAMINO DERIVATIVES USEFUL FOR THE TREATMENT OF CERTAIN INFLAMMATORY DISORDERS | NEUROSEARCH A/S (DK) | 2010-06-09 | — | — | EP | claimed |
| WO-2009027292-A1 | CARBONYLAMINO DERIVATIVES USEFUL FOR THE TREATMENT OF CERTAIN INFLAMMATORY DISORDERS | NEUROSEARCH A/S (DK) | 2009-03-05 | — | — | WO | claimed |
| WO-2003004010-A1 | CARBONYLAMINO DERIVATIVES USEFUL FOR OBTAINING IMMUNE REGULATION | POSEIDON PHARMACEUTICALS A/S (DK) | 2003-01-16 | — | — | WO | claimed |
| EP-0316820-B1 | THIAZOLE COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-01-22 | — | — | EP | claimed |
| US-4921887-A | ANTIALLERGENS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-05-01 | — | — | US | claimed |
| CN-119246718-A | Chiral analysis method of semaglutin series intermediates | 杭州澳赛诺医药技术有限公司 | 2025-01-03 | — | — | CN | disclosed |
| US-20230248672-A1 | COMPOSITIONS COMPRISING GARDOS CHANNEL ANTAGONISTS AND THEIR USES | ADIMABIO LLC (US) | 2023-08-10 | — | — | US | disclosed |
| US-20230248672-A1 | COMPOSITIONS COMPRISING GARDOS CHANNEL ANTAGONISTS AND THEIR USES | ADIMABIO LLC (US) | 2023-08-10 | — | — | US | disclosed |
| US-20230248672-A1 | COMPOSITIONS COMPRISING GARDOS CHANNEL ANTAGONISTS AND THEIR USES | ADIMABIO LLC (US) | 2023-08-10 | — | — | US | disclosed |
| EP-4181908-A2 | COMPOSITIONS COMPRISING GARDOS CHANNEL ANTAGONISTS AND THEIR USES | Adimabio LLC (US) | 2023-05-24 | — | — | EP | disclosed |
| EP-4181908-A2 | COMPOSITIONS COMPRISING GARDOS CHANNEL ANTAGONISTS AND THEIR USES | Adimabio LLC (US) | 2023-05-24 | — | — | EP | disclosed |
| EP-1158971-A1 | GARDOS CHANNEL ANTAGONISTS | Icagen, Inc. (US) | 2001-12-05 | — | — | EP | disclosed |
| US-6288122-B1 | A TRIPHENYL ACETAMIDE | ICAGEN, INC. | 2001-09-11 | — | — | US | disclosed |
| WO-2000050026-A1 | GARDOS CHANNEL ANTAGONISTS | ICAGEN, INC. (US) | 2000-08-31 | — | — | WO | disclosed |
| EP-0316820-B1 | THIAZOLE COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-01-22 | — | — | EP | disclosed |
| EP-0444068-A1 | TRIALKYSILYL ESTERS OF AMINO ACIDS AND THEIR USE IN THE SYNTHESIS OF PEPTIDES | PUBLIC HEALTH LABORATORY SERVICE BOARD (GB) | 1991-09-04 | — | — | EP | disclosed |
| WO-1990005738-A1 | TRIALKYSILYL ESTERS OF AMINO ACIDS AND THEIR USE IN THE SYNTHESIS OF PEPTIDES | PUBLIC HEALTH LABORATORY SERVICE BOARD (GB) | 1990-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230248672-A1 | COMPOSITIONS COMPRISING GARDOS CHANNEL ANTAGONISTS AND THEIR USES | CACNA1G, CACNA1I, CACNG2 | KCNN4 36/4885MAPT 4593/4885KMT2A 1832/4885 |
| US-20110124735-A1 | CARBONYLAMINO DERIVATIVES USEFUL FOR THE TREATMENT OF CERTAIN INFLAMMATORY DISORDERS | NFKBIA, TNF, LTC4S | KCNN4 4646/4885MAPT 1906/4885KMT2A 2992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.