SCHEMBL10360792

SCHEMBL10360792

Cc1ccc(Oc2cccc(COCC(Cl)(Cl)Cl)n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RX3 P56373 9/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
NPC1 O15118 3/20 0.38
RAB9A P51151 2/20 0.38
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38
HTT P42858 1/20 0.38
ATM Q13315 1/20 0.38
MAP4K4 O95819 1/20 0.36
LMNA P02545 2/20 0.34
KDM4E B2RXH2 1/20 0.34
F2 P00734 1/20 0.33
F10 P00742 1/20 0.33
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33
PRSS3 P35030 1/20 0.33
ST14 Q9Y5Y6 1/20 0.33
PPARG P37231 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10360778 0.91 P2RX3 (0.39) P2RX3MEN1KMT2ANPC1RAB9A
SCHEMBL10360700 0.89 NPC1 (0.38) P2RX3MEN1KMT2ANPC1RAB9A
SCHEMBL10362155 0.88 MEN1 (0.40) P2RX3MEN1KMT2ANPC1RAB9A
SCHEMBL10361374 0.88 MRGPRX4 (0.40) P2RX3MEN1KMT2AHTTATM
SCHEMBL10361286 0.87 KCNH2 (0.44) P2RX3NPC1RAB9AALDH1A1HTT
SCHEMBL10361871 0.87 SMN1; SMN2 (0.41) P2RX3NPC1RAB9AALDH1A1F2
SCHEMBL10360763 0.86 F2 (0.33) P2RX3NPC1RAB9AHPGDKDM4E
SCHEMBL10360899 0.86 MEN1 (0.39) P2RX3MEN1KMT2AALDH1A1HTT
SCHEMBL10361929 0.78 P2RX3 (0.39) P2RX3MEN1KMT2AHTTTSHR
SCHEMBL10361288 0.78 KDM4E (0.36) LMNAKDM4ENPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0175377-B1 AN ETHER COMPOUND, ITS PRODUCTION AND AN INSECTICIDAL AND ACARICIDAL COMPOSITION CONTAINING IT AS AN ACTIVE INGREDIENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-11-28 EP disclosed
US-4664698-A Ether compound, and an insecticidal and acaricidal composition containing it as an active ingredient SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-05-12 US disclosed
EP-0175377-A2 An ether compound, its production and an insecticidal and acaricidal composition containing it as an active ingredient SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-03-26 EP disclosed