SCHEMBL10360899

SCHEMBL10360899

Fc1ccc(Oc2cccc(COCC(Cl)(Cl)Cl)n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
HTT P42858 1/20 0.38
P2RX3 P56373 5/20 0.35
ALDH1A1 P00352 2/20 0.34
POLB P06746 1/20 0.34
ATM Q13315 1/20 0.34
F2 P00734 1/20 0.33
F10 P00742 1/20 0.33
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33
PRSS3 P35030 1/20 0.33
ST14 Q9Y5Y6 1/20 0.33
KDM4E B2RXH2 1/20 0.33
PPARG P37231 1/20 0.32
LOXL2 Q9Y4K0 1/20 0.32
CHRM5 P08912 1/20 0.32
SCN9A Q15858 1/20 0.32
HSD17B14 Q9BPX1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10361374 0.88 MRGPRX4 (0.40) MEN1KMT2AL3MBTL1HTTP2RX3
SCHEMBL10361286 0.87 KCNH2 (0.44) L3MBTL1HTTP2RX3ALDH1A1F2
SCHEMBL10360792 0.86 P2RX3 (0.39) MEN1KMT2AHTTP2RX3ALDH1A1
SCHEMBL10360700 0.86 NPC1 (0.38) MEN1KMT2AL3MBTL1HTTP2RX3
SCHEMBL10360868 0.86 MEN1 (0.38) MEN1KMT2AL3MBTL1HTTP2RX3
SCHEMBL10360763 0.86 F2 (0.33) P2RX3F2F10PRSS1PRSS2
SCHEMBL10361871 0.84 SMN1; SMN2 (0.41) L3MBTL1P2RX3ALDH1A1F2F10
SCHEMBL10362256 0.82
SCHEMBL10361874 0.82 MAP4K4 (0.41) MAPK14
SCHEMBL10361288 0.78 KDM4E (0.36) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0175377-B1 AN ETHER COMPOUND, ITS PRODUCTION AND AN INSECTICIDAL AND ACARICIDAL COMPOSITION CONTAINING IT AS AN ACTIVE INGREDIENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-11-28 EP disclosed
US-4664698-A Ether compound, and an insecticidal and acaricidal composition containing it as an active ingredient SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-05-12 US disclosed
EP-0175377-A2 An ether compound, its production and an insecticidal and acaricidal composition containing it as an active ingredient SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-03-26 EP disclosed