Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 8/20 | 0.43 |
| ▸ | NPC1 | O15118 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11803015 | 0.92 | ALDH1A1 (0.51) | ALDH1A1GAATDP1RAB9ANPC1 | |
| SCHEMBL45414 | 0.92 | ALDH1A1 (0.51) | ALDH1A1GAATDP1RAB9ANPC1 | |
| SCHEMBL10360645 | 0.89 | ALDH1A1 (0.42) | ALDH1A1GAATDP1RAB9ANPC1 | |
| SCHEMBL9003688 | 0.89 | HDAC8 (0.46) | RAB9ANPC1SMN1; SMN2HPGDLMNA | |
| SCHEMBL10361290 | 0.87 | ALDH1A1 (0.57) | ALDH1A1GAATDP1RAB9ANPC1 | |
| SCHEMBL10360223 | 0.84 | RAB9A (0.53) | ALDH1A1RAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL8601031 | 0.83 | CSNK2A2 (0.43) | ALDH1A1GAATDP1RAB9ANPC1 | |
| SCHEMBL10775979 | 0.82 | ALDH1A1 (0.51) | ALDH1A1GAATDP1RAB9ANPC1 | |
| SCHEMBL27811403 | 0.81 | GAA (0.47) | ALDH1A1GAATDP1RAB9ANPC1 | |
| SCHEMBL10360208 | 0.80 | NPC1 (0.56) | ALDH1A1RAB9ANPC1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0247476-B1 | HYDROXYPHENYL URETHANES, PROCESS FOR THEIR MANUFACTURE, THEIR USES AND CHLOROFORMATES COMPRISING HYDROXYPHENYL URETHANE GROUPS | BAYER AG (DE) | 1990-12-27 | — | — | EP | disclosed |
| EP-0247483-A2 | Process for the preparation of hydroxyphenyl urethanes | BAYER AG (DE) | 1987-12-02 | — | — | EP | disclosed |
| EP-0247476-A1 | Hydroxyphenyl urethanes, process for their manufacture, their uses and chloroformates comprising hydroxyphenyl urethane groups | BAYER AG (DE) | 1987-12-02 | — | — | EP | disclosed |