SCHEMBL10360944

SCHEMBL10360944

CCCCCCCCCCC(=O)C(C)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.57
GPR84 Q9NQS5 6/20 0.54
PPARG P37231 6/20 0.54
PPARD Q03181 6/20 0.54
PPARA Q07869 6/20 0.54
HDAC11 Q96DB2 5/20 0.54
TSHR P16473 4/20 0.54
ALDH1A1 P00352 2/20 0.54
TLR2 O60603 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
FABP4 P15090 2/20 0.54
PTPN1 P18031 2/20 0.54
SLC22A6 Q4U2R8 1/20 0.54
SLC22A8 Q8TCC7 1/20 0.54
MEN1 O00255 1/20 0.54
ESR1 P03372 1/20 0.54
ALOX15 P16050 1/20 0.54
PDE4A P27815 1/20 0.54
KMT2A Q03164 1/20 0.54
PDE3A Q14432 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8637203 1.00 CES2 (0.57) CES2GPR84PPARGPPARDPPARA
SCHEMBL28823312 1.00 CES2 (0.57) CES2GPR84PPARGPPARDPPARA
SCHEMBL18528772 1.00 CES2 (0.57) CES2GPR84PPARGPPARDPPARA
SCHEMBL19732886 1.00 CES2 (0.57) CES2GPR84PPARGPPARDPPARA
SCHEMBL8780156 1.00 CES2 (0.57) CES2GPR84PPARGPPARDPPARA
SCHEMBL28923381 1.00 CES2 (0.57) CES2GPR84PPARGPPARDPPARA
Ammonia Solution, Strong SCHEMBL27577496 0.98 CES2 (0.55) CES2GPR84PPARGPPARDPPARA
SCHEMBL3142041 0.98 CES2 (0.54) CES2GPR84PPARGPPARDPPARA
SCHEMBL2411791 0.91 CES2 (0.46) CES2ALDH1A1MEN1KMT2A
SCHEMBL5528500 0.91 CES2 (0.46) CES2ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0252880-B1 HYDROXYPHOSPHONO CARBOXYLIC ACIDS CIBA-GEIGY AG (CH) 1990-11-28 EP disclosed
US-4847017-A CORROSION RESISTANCE IN WATER SYSTEMS CIGA-GEIGY CORPORATION (US) 1989-07-11 US disclosed
EP-0252880-A2 Hydroxyphosphono carboxylic acids CIBA-GEIGY AG (CH) 1988-01-13 EP disclosed