Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.57 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.54 |
| ▸ | PPARG | P37231 | 6/20 | 0.54 |
| ▸ | PPARD | Q03181 | 6/20 | 0.54 |
| ▸ | PPARA | Q07869 | 6/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TLR2 | O60603 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | FABP4 | P15090 | 2/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.54 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | PDE4A | P27815 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8637203 | 1.00 | CES2 (0.57) | CES2GPR84PPARGPPARDPPARA | |
| SCHEMBL28823312 | 1.00 | CES2 (0.57) | CES2GPR84PPARGPPARDPPARA | |
| SCHEMBL18528772 | 1.00 | CES2 (0.57) | CES2GPR84PPARGPPARDPPARA | |
| SCHEMBL8780156 | 1.00 | CES2 (0.57) | CES2GPR84PPARGPPARDPPARA | |
| SCHEMBL28923381 | 1.00 | CES2 (0.57) | CES2GPR84PPARGPPARDPPARA | |
| SCHEMBL10360944 | 1.00 | CES2 (0.57) | CES2GPR84PPARGPPARDPPARA | |
| Ammonia Solution, Strong SCHEMBL27577496 | 0.98 | CES2 (0.55) | CES2GPR84PPARGPPARDPPARA | |
| SCHEMBL3142041 | 0.98 | CES2 (0.54) | CES2GPR84PPARGPPARDPPARA | |
| SCHEMBL2411791 | 0.91 | CES2 (0.46) | CES2ALDH1A1MEN1KMT2A | |
| SCHEMBL5528500 | 0.91 | CES2 (0.46) | CES2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11596626-B2 | Compound for use against pathogenic Neisseria and Haemophilus species and Moraxella catarrhalis | Universität Konstanz (DE) | 2023-03-07 | — | — | US | disclosed |
| EP-3475260-B1 | COMPOUNDS FOR USE AS AN ANTI-BACTERIAL OR ANTI-FUNGAL AGENT AND AS A ZINC SENSOR | UNIV KONSTANZ (DE) | 2022-03-30 | — | — | EP | disclosed |
| US-20210169869-A1 | Compound for Use Against Pathogenic Neisseria and Haemophilus Species and Moraxella Catarrhalis | Universität Wien (AT) | 2021-06-10 | — | — | US | disclosed |
| US-10961196-B2 | Compounds for use as an anti-bacterial or anti-fungal agent and as a zinc sensor | Universität Konstanz (DE) | 2021-03-30 | — | — | US | disclosed |
| EP-3728193-A1 | COMPOUND FOR USE AGAINST PATHOGENIC NEISSERIA AND HAEMOPHILUS SPECIES AND MORAXELLA CATARRHALIS | Universität Konstanz (DE) | 2020-10-28 | — | — | EP | disclosed |
| US-20190218183-A1 | COMPOUNDS FOR USE AS AN ANTI-BACTERIAL OR ANTI-FUNGAL AGENT AND AS A ZINC SENSOR | Universität Konstanz (DE) | 2019-07-18 | — | — | US | disclosed |
| EP-3502095-A1 | COMPOUND FOR USE AGAINST PATHOGENIC NEISSERIA AND HAEMOPHILUS SPECIES AND MORAXELLA CATARRHALIS | Universität Konstanz (DE) | 2019-06-26 | — | — | EP | disclosed |
| EP-3475260-A1 | COMPOUNDS FOR USE AS AN ANTI-BACTERIAL OR ANTI-FUNGAL AGENT AND AS A ZINC SENSOR | Universität Konstanz (DE) | 2019-05-01 | — | — | EP | disclosed |
| WO-2017220205-A1 | COMPOUNDS FOR USE AS AN ANTI-BACTERIAL OR ANTI-FUNGAL AGENT AND AS A ZINC SENSOR | Universität Konstanz (DE) | 2017-12-28 | — | — | WO | disclosed |
| EP-3260445-A1 | COMPOUNDS FOR USE AS AN ANTI-BACTERIAL OR ANTI-FUNGAL AGENT AND AS A ZINC SENSOR | Universität Konstanz (DE) | 2017-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11596626-B2 | Compound for use against pathogenic Neisseria and Haemophilus species and Moraxella catarrhalis | MLEC, MPO, B3GNT2 | CES2 3410/4885GPR84 2107/4885PPARG 1344/4885 |
| US-20190218183-A1 | COMPOUNDS FOR USE AS AN ANTI-BACTERIAL OR ANTI-FUNGAL AGENT AND AS A ZINC SENSOR | ZFR, ZC3HAV1, ZFX | CES2 4210/4885GPR84 1225/4885PPARG 2261/4885 |
| US-10961196-B2 | Compounds for use as an anti-bacterial or anti-fungal agent and as a zinc sensor | ZFR, ZC3HAV1, ZFX | CES2 4210/4885GPR84 1225/4885PPARG 2261/4885 |
| US-20210169869-A1 | Compound for Use Against Pathogenic Neisseria and Haemophilus Species and Moraxella Catarrhalis | MLEC, MPO, B3GNT2 | CES2 3410/4885GPR84 2107/4885PPARG 1344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.