Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10360611 | 0.94 | RAB9A (0.55) | RAB9AHPGDLMNAEPHX2NPC1 | |
| SCHEMBL11422530 | 0.89 | RAB9A (0.53) | RAB9AHPGDLMNAEPHX2NPC1 | |
| SCHEMBL11431792 | 0.86 | HPGD (0.71) | RAB9AHPGDLMNAEPHX2NPC1 | |
| SCHEMBL10361292 | 0.85 | HPGD (0.56) | RAB9AHPGDLMNAEPHX2NPC1 | |
| SCHEMBL10360620 | 0.83 | HPGD (0.54) | RAB9AHPGDLMNAEPHX2NPC1 | |
| SCHEMBL1933135 | 0.82 | MAPK1 (0.68) | RAB9AHPGDLMNAEPHX2NPC1 | |
| SCHEMBL17263428 | 0.81 | RAB9A (0.75) | RAB9AHPGDLMNANPC1SMN1; SMN2 | |
| SCHEMBL10817231 | 0.81 | RAB9A (0.75) | RAB9AHPGDLMNANPC1SMN1; SMN2 | |
| SCHEMBL832082 | 0.80 | RAB9A (0.64) | RAB9AHPGDLMNAEPHX2NPC1 | |
| SCHEMBL29687812 | 0.80 | RAB9A (0.64) | RAB9AHPGDLMNAEPHX2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0247476-B1 | HYDROXYPHENYL URETHANES, PROCESS FOR THEIR MANUFACTURE, THEIR USES AND CHLOROFORMATES COMPRISING HYDROXYPHENYL URETHANE GROUPS | BAYER AG (DE) | 1990-12-27 | — | — | EP | disclosed |
| EP-0247483-A2 | Process for the preparation of hydroxyphenyl urethanes | BAYER AG (DE) | 1987-12-02 | — | — | EP | disclosed |
| EP-0247476-A1 | Hydroxyphenyl urethanes, process for their manufacture, their uses and chloroformates comprising hydroxyphenyl urethane groups | BAYER AG (DE) | 1987-12-02 | — | — | EP | disclosed |