Sugi Predict

Sugi Predict / Compounds / SCHEMBL1933135

SCHEMBL1933135

SCHEMBL1933135

CCOC(=O)Nc1cccc(O)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 2/20 0.68
▸ LMNA P02545 1/20 0.68
▸ MAPT P10636 1/20 0.68
▸ HSD17B10 Q99714 1/20 0.68
▸ ALDH1A1 P00352 2/20 0.64
▸ CYP1A2 P05177 2/20 0.59
▸ NPC1 O15118 3/20 0.58
▸ SMN1; SMN2 Q16637 2/20 0.58
▸ HTT P42858 1/20 0.58
▸ F2R P25116 1/20 0.58
▸ EPHX2 P34913 1/20 0.58
▸ MTNR1B P49286 1/20 0.56
▸ POLB P06746 1/20 0.55
▸ HPGD P15428 3/20 0.55
▸ NLRP3 Q96P20 3/20 0.55
▸ RAB9A P51151 2/20 0.55
▸ CYP2C9 P11712 1/20 0.55
▸ CYP2C19 P33261 1/20 0.55
▸ GAA P10253 1/20 0.54
▸ CRHBP P24387 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7565149 0.90 MAPK1 (0.81) MAPK1LMNAMAPTHSD17B10ALDH1A1
SCHEMBL11431792 0.87 HPGD (0.71) MAPK1LMNAMAPTHSD17B10ALDH1A1
SCHEMBL7565151 0.85 MAPK1 (0.79) MAPK1LMNAMAPTHSD17B10ALDH1A1
SCHEMBL3424143 0.85 MAPK1 (0.69) MAPK1LMNAMAPTHSD17B10ALDH1A1
SCHEMBL10937909 0.83 LMNA (0.60) MAPK1LMNAMAPTHSD17B10ALDH1A1
SCHEMBL8017782 0.82 ALDH1A1 (0.67) MAPK1MAPTHSD17B10ALDH1A1CYP1A2
SCHEMBL29355426 0.82 ALDH1A1 (0.67) MAPK1MAPTHSD17B10ALDH1A1CYP1A2
SCHEMBL3117227 0.82 MAPK1 (0.66) MAPK1LMNAMAPTHSD17B10ALDH1A1
SCHEMBL21349100 0.82 MAPK1 (0.66) MAPK1LMNAMAPTHSD17B10ALDH1A1
SCHEMBL1188378 0.82 MAPT (0.66) MAPK1LMNAMAPTHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118878497-A Coumarin derivative containing amide bond and preparation method and application thereof 宁波大学 2024-11-01 — — CN claimed
CN-111925348-A Coumarin Schiff base derivative and preparation method and application thereof 贵州民族大学 2020-11-13 — — CN claimed
EP-0142670-B1 A PROCESS FOR THE PREPARATION OF KNOWN HERBICIDALLY ACTIVE PHENYL CARBAMATES BEROL NOBEL (SUISSE) S.A. (CH) 1990-05-23 — — EP claimed
EP-0142670-A2 A process for the preparation of known herbicidally active phenyl carbamates BEROL NOBEL (SUISSE) S.A. (CH) 1985-05-29 — — EP claimed
WO-1985001286-A1 A PROCESS FOR THE PREPARATION OF HERBICIDALLY ACTIVE PHENYL CARBAMATES AND HERBICIDAL COMPOSITIONS CONTAINING THE SAME KEMISK VA^ERK KO^/GE A/S (DK) 1985-03-28 — — WO claimed
US-4103086-A 8-Oxo-4-thia-1-azabicyclo (4.2.0)-oct-2-ene derivatives SMITHKLINE CORPORATION (US) 1978-07-25 — — US claimed
US-4084056-A FROM AN AROMATIC AMIDE AND A GROUP IA OR IIA HYPOCHLORITE WITH A CARBAMATE SUBSTITUTED PHENOL AB BOFORS (SW) 1978-04-11 — — US claimed
US-20250326732-A1 CHROMEN-2-ONE MODULATORS OF POLRMT PRETZEL THERAPEUTICS, INC. (US) 2025-10-23 — — US disclosed
CN-118878497-A Coumarin derivative containing amide bond and preparation method and application thereof 宁波大学 2024-11-01 — — CN disclosed
WO-2023034346-A1 CHROMEN-2-ONE MODULATORS OF POLRMT PRETZEL THERAPEUTICS, INC. (US) 2023-03-09 — — WO disclosed
CN-113474156-B Polyamic acid resin composition, polyimide resin film and method for producing same, laminate, and electronic device and method for producing same 东丽株式会社 2022-04-29 — — CN disclosed
US-20210352892-A1 MACROMOLECULAR AND NONPARTICULATE AGROCHEMICALS TO REDUCE VAPOR DRIFT UNIVERSITY OF UTAH RESEARCH FOUNDATION 2021-11-18 — — US disclosed
CN-113474156-A Polyamic acid resin composition, polyimide resin film and method for producing same, laminate, and electronic device and method for producing same 东丽株式会社 2021-10-01 — — CN disclosed
US-4267280-A Controlled release pesticides and method of preparation HOPKINS, MADISON WISCONSIN A CORP OF WISCONSIN 1981-05-12 — — US disclosed
EP-0018581-A1 Process for the preparation of aryl-mono- and/or polyurethanes BASF Aktiengesellschaft (DE) 1980-11-12 — — EP disclosed
US-4229208-A Diurethanes with selective herbicidal action SCHERING AG (DE) 1980-10-21 — — US disclosed
US-4225693-A CONTROLLED RELEASE HOPKINS AGRICULTURAL CHEMICAL COMPANY 1980-09-30 — — US disclosed
US-4164414-A N-methylcarbanilic-[3-(ethoxycarbonylamino)-phenyl]-ester as a cotton herbicide SCHERING AKTIENGESELLSCHAFT (DE) 1979-08-14 — — US disclosed
US-4131751-A PHENYLENE, PLANT GROWTH REGULATORS BASF AKTIENGESELLSCHAFT (DE) 1978-12-26 — — US disclosed
US-4084056-A FROM AN AROMATIC AMIDE AND A GROUP IA OR IIA HYPOCHLORITE WITH A CARBAMATE SUBSTITUTED PHENOL AB BOFORS (SW) 1978-04-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250326732-A1 CHROMEN-2-ONE MODULATORS OF POLRMT POLRMT, TFAM, POLM MAPK1 2069/4885LMNA 2115/4885MAPT 716/4885
US-20210352892-A1 MACROMOLECULAR AND NONPARTICULATE AGROCHEMICALS TO REDUCE VAPOR DRIFT ACP1, PTMS, VDAC1 MAPK1 4336/4885LMNA 3816/4885MAPT 806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.