Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ACP1 | P24666 | 2/20 | 0.35 |
| ▸ | CDC25B | P30305 | 2/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730908 | 0.81 | — | — | |
| SCHEMBL91068 | 0.71 | PTPN1 (0.43) | PTPN1ALDH1A1LMNAHSD17B10HTT | |
| SCHEMBL18957266 | 0.71 | — | — | |
| SCHEMBL12041925 | 0.69 | ALDH1A1 (0.45) | PTPN1ALDH1A1LMNAHSD17B10CRHBP | |
| SCHEMBL5117712 | 0.69 | — | — | |
| SCHEMBL17603303 | 0.67 | PTPN1 (0.33) | PTPN1LMNAGAAKMT2A | |
| SCHEMBL7137575 | 0.67 | — | — | |
| SCHEMBL10572506 | 0.67 | PTPN1 (0.40) | PTPN1ALDH1A1LMNAHSD17B10HTT | |
| SCHEMBL5171537 | 0.67 | PTPN1 (0.45) | PTPN1ALDH1A1LMNACRHBPCRHR2 | |
| SCHEMBL18098832 | 0.67 | ALDH1A1 (0.44) | PTPN1ALDH1A1CRHBPCRHR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0139614-B1 | PHARMACEUTICAL PREPARATIONS CONTAINING FLAVANONE OR THIOFLAVANONE DERIVATIVES, THE USE THEREOF, NOVEL FLAVANONES AND THIOFLAVANONES, AND PROCESSES FOR THEIR MANUFACTURE | Zyma SA (CH) | 1990-08-22 | — | — | EP | disclosed |
| US-4935441-A | Flavene and thioflavene derivates, processes for their manufacture, pharmaceutical preparations that contain such compounds, and the use of the latter | ZYMA SA (CH) | 1990-06-19 | — | — | US | disclosed |
| US-4885298-A | Pharmaceutical preparations containing flavanone or thioflavanone derivatives the use thereof, novel flavanones and thioflavanones, and processes for their manufacture | ZYMA SA (CH) | 1989-12-05 | — | — | US | disclosed |
| EP-0140830-B1 | PHARMACEUTICAL PREPARATIONS CONTAINING FLAVENE OR THIOFLAVENE DERIVATIVES, THE USE THEREOF, NOVEL FLAVENES AND THIOFLAVENES, AND PROCESSES FOR THEIR MANUFACTURE | Zyma SA (CH) | 1989-08-30 | — | — | EP | disclosed |
| EP-0096007-B1 | PHARMACEUTICAL PREPARATIONS CONTAINING (+)-CYANIDAN-3-OL DERIVATIVES, THE USE THEREOF, NOVEL SUBSTITUTED (+)-CYANIDAN-3-OL DERIVATIVES, AND PROCESSES FOR PRODUCING THEM | Zyma SA (CH) | 1987-07-29 | — | — | EP | disclosed |
| US-4665202-A | Flavene and thioflavene derivatives | ZYMA SA (CH) | 1987-05-12 | — | — | US | disclosed |
| US-4644011-A | LIVER AND VIEN DISORDERS | ZYMA SA (CH) | 1987-02-17 | — | — | US | disclosed |
| EP-0140830-A2 | Pharmaceutical preparations containing flavene or thioflavene derivatives, the use thereof, novel flavenes and thioflavenes, and processes for their manufacture | Zyma SA (CH) | 1985-05-08 | — | — | EP | disclosed |
| EP-0139615-A2 | Flavene and thioflavene derivatives, processes for their manufacture, pharmaceutical preparations that contain such compounds, and the use of the latter | Zyma SA (CH) | 1985-05-02 | — | — | EP | disclosed |
| EP-0139614-A2 | Pharmaceutical preparations containing flavanone or thioflavanone derivatives, the use thereof, novel flavanones and thioflavanones, and processes for their manufacture | Zyma SA (CH) | 1985-05-02 | — | — | EP | disclosed |
| US-4510159-A | (+)-Cyanidan-3-ol derivatives, pharmaceutical preparations that contain such compounds, and the use of the latter to treat liver or venous diseases | ZYMA SA (CH) | 1985-04-09 | — | — | US | disclosed |
| EP-0096007-A2 | Pharmaceutical preparations containing (+)-cyanidan-3-ol derivatives, the use thereof, novel substituted (+)-cyanidan-3-ol derivatives, and processes for producing them | Zyma SA (CH) | 1983-12-07 | — | — | EP | disclosed |
| EP-0096008-A2 | (+)-Cyanidan-3-ol derivatives, processes for their manufacture, pharmaceutical preparations that contain such compounds, and the use of the latter | Zyma SA (CH) | 1983-12-07 | — | — | EP | disclosed |