Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14572679 | 0.79 | PTPN1 (0.42) | ALDH1A1CRHBPCRHR2PTPN1KMT2A | |
| SCHEMBL9730908 | 0.78 | — | — | |
| SCHEMBL18098832 | 0.76 | ALDH1A1 (0.44) | ALDH1A1CRHBPCRHR2PTPN1TSHR | |
| SCHEMBL5171537 | 0.76 | PTPN1 (0.45) | ALDH1A1CRHBPCRHR2PTPN1TSHR | |
| SCHEMBL14572632 | 0.74 | SIRT1 (0.59) | ALDH1A1CRHBPCRHR2SMN1; SMN2CYP1A2 | |
| SCHEMBL13416911 | 0.74 | ALDH1A1 (0.47) | ALDH1A1CRHBPCRHR2PTPN1SMN1; SMN2 | |
| SCHEMBL13467414 | 0.72 | ALDH1A1 (0.42) | ALDH1A1CRHBPCRHR2PTPN1TSHR | |
| SCHEMBL21218107 | 0.72 | ALDH1A1 (0.55) | ALDH1A1TSHRSMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL7137074 | 0.72 | ALDH1A1 (0.47) | ALDH1A1CRHBPCRHR2PTPN1TSHR | |
| SCHEMBL3077632 | 0.72 | PTPN1 (0.47) | ALDH1A1CRHBPCRHR2PTPN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024103067-A1 | COMPOUNDS AND COMPOSITIONS AS eIF4E INHIBITORS AND USES THEREOF | RIBOMETRIX, INC. (US) | 2024-05-16 | — | — | WO | disclosed |
| EP-3664900-B1 | PHOTOSENSITIVE MICROCAPSULES | PROCTER & GAMBLE INT OPERATIONS SA (CH) | 2023-08-23 | — | — | EP | disclosed |
| US-20220144769-A1 | COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2022-05-12 | — | — | US | disclosed |
| EP-3441115-B1 | PHOTOSENSITIVE MICROCAPSULES | PROCTER & GAMBLE INT OPERATIONS SA (CH) | 2020-05-27 | — | — | EP | disclosed |
| EP-3441115-A1 | PHOTOSENSITIVE MICROCAPSULES | Procter & Gamble International Operations SA (CH) | 2019-02-13 | — | — | EP | disclosed |
| US-9840512-B2 | Antidiabetic bicyclic compounds | MERCK SHARP & DOHME CORP. (US) | 2017-12-12 | — | — | US | disclosed |
| US-9840512-B2 | Antidiabetic bicyclic compounds | MERCK SHARP & DOHME CORP. (US) | 2017-12-12 | — | — | US | disclosed |
| US-9290623-B2 | Composition for forming silicon-containing resist underlayer film having cyclic diester group | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2016-03-22 | — | — | US | disclosed |
| US-20160002255-A1 | ANTIDIABETIC BICYCLIC COMPOUNDS | MERCK SHARP & DOHME LLC | 2016-01-07 | — | — | US | disclosed |
| US-20160002255-A1 | ANTIDIABETIC BICYCLIC COMPOUNDS | MERCK SHARP & DOHME LLC | 2016-01-07 | — | — | US | disclosed |
| US-8003662-B2 | Heterobicyclic thiophene compounds and methods of use | ARRAY BIOPHARMA, INC. (US) | 2011-08-23 | — | — | US | disclosed |
| US-20100256356-A1 | HETEROBICYCLIC PYRAZOLE COMPOUNDS AND METHODS OF USE | ARRAY BIOPHARMA INC. (US) | 2010-10-07 | — | — | US | disclosed |
| US-7723330-B2 | Heterobicyclic pyrazole compounds and methods of use | ARRAY BIOPHARMA INC. (US) | 2010-05-25 | — | — | US | disclosed |
| US-20090029093-A1 | OPTICAL INFORMATION RECORDING MEDIUM AND PROCESS FOR PRODUCING THE SAME | FUJIFILM CORPORATION (JP) | 2009-01-29 | — | — | US | disclosed |
| US-20080312273-A1 | Quinoline Derivatives Having Vegf Inhibiting Activity | HENNEQUIN LAURENT FRANCOIS ANDRE | 2008-12-18 | — | — | US | disclosed |
| US-7371765-B2 | Quinoline derivatives having VEGF inhibiting activity | ASTRAZENECA AB (SE) | 2008-05-13 | — | — | US | disclosed |
| US-20070238726-A1 | Heterobicyclic pyrazole compounds and methods of use | GENENTECH, INC. | 2007-10-11 | — | — | US | disclosed |
| US-20070197537-A1 | Heterobicyclic thiophene compounds and methods of use | ARRAY BIOPHARMA, INC. | 2007-08-23 | — | — | US | disclosed |
| US-7230017-B2 | Dihydropyridinone derivatives | BAYER HEALTHCARE AG (DE) | 2007-06-12 | — | — | US | disclosed |
| US-20070059641-A1 | Optical recording medium and polymethine complex for use in the recording layer of the optical recording medium | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE | 2007-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197537-A1 | Heterobicyclic thiophene compounds and methods of use | ERBB2, LCK, SRC | ALDH1A1 1635/4885CRHBP 3456/4885CRHR2 1602/4885 |
| US-20220144769-A1 | COMPOUND | CBR3, SFXN3, CBR1 | ALDH1A1 928/4885CRHBP 2334/4885CRHR2 1189/4885 |
| US-20080312273-A1 | Quinoline Derivatives Having Vegf Inhibiting Activity | VEGFA, FLT1, FLT4 | ALDH1A1 1187/4885CRHBP 3762/4885CRHR2 2445/4885 |
| US-20100256356-A1 | HETEROBICYCLIC PYRAZOLE COMPOUNDS AND METHODS OF USE | ROR1, CYP11B1, CYP11B2 | ALDH1A1 1929/4885CRHBP 2164/4885CRHR2 639/4885 |
| US-20070238726-A1 | Heterobicyclic pyrazole compounds and methods of use | ROR1, CYP11B1, CYP11B2 | ALDH1A1 1929/4885CRHBP 2164/4885CRHR2 639/4885 |
| US-20160002255-A1 | ANTIDIABETIC BICYCLIC COMPOUNDS | GPR119, GPR65, GLP1R | ALDH1A1 2872/4885CRHBP 1329/4885CRHR2 454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.