Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5971626 | 0.95 | TSHR (0.58) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL5448469 | 0.92 | TSHR (0.47) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL8068594 | 0.91 | TSHR (0.54) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| Methacrylic Acid SCHEMBL27531007 | 0.88 | TSHR (0.50) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| Acrylic Acid SCHEMBL27810281 | 0.88 | TSHR (0.50) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL5080728 | 0.88 | TSHR (0.44) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL424597 | 0.88 | TSHR (0.44) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL6654168 | 0.88 | TSHR (0.41) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL27810283 | 0.87 | TSHR (0.49) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL28246671 | 0.87 | TSHR (0.43) | TSHRHPGDALDH1A1CYP3A4THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2276836-A1 | SURFACES WITH IMMOBILIZED ENZYMES OR ANTI-ICING PROTEINS | Airbus Operations Limited (GB) | 2011-01-26 | — | — | EP | disclosed |
| WO-2009136186-A1 | SURFACES WITH IMMOBILIZED ENZYMES OR ANTI-ICING PROTEINS | AIRBUS UK LIMITED (GB) | 2009-11-12 | — | — | WO | disclosed |