Methacrylic Acid

Methacrylic Acid

SCHEMBL27531007

C=C(C)C(=O)O.C=C(C)C(=O)OC.C=C(C)C(=O)OCCC[Si](OC)(OC)OC.C=CC(=O)OCCCC

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 10/20 0.50
HPGD P15428 1/20 0.50
ALDH1A1 P00352 5/20 0.37
CYP3A4 P08684 1/20 0.37
ATM Q13315 1/20 0.36
HCAR2 Q8TDS4 3/20 0.36
POLB P06746 1/20 0.34
APEX1 P27695 1/20 0.34
HTT P42858 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
THRB P10828 2/20 0.34
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TP53 P04637 2/20 0.31
HIF1A Q16665 2/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8068594 0.96 TSHR (0.54) TSHRHPGDALDH1A1CYP3A4ATM
Acrylic Acid SCHEMBL27810281 0.95 TSHR (0.50) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL5971626 0.93 TSHR (0.58) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL27810283 0.92 TSHR (0.49) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL23120125 0.89 TSHR (0.46) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL1036154 0.88 TSHR (0.56) TSHRHPGDALDH1A1CYP3A4ATM
Acrylic Acid Ethyl Ester SCHEMBL4457688 0.88 TSHR (0.42) TSHRHPGDALDH1A1CYP3A4POLB
SCHEMBL5448469 0.88 TSHR (0.47) TSHRHPGDALDH1A1CYP3A4ATM
Methacrylic Acid SCHEMBL2018446 0.88 TSHR (0.65) TSHRHPGDALDH1A1CYP3A4ATM
Styrene SCHEMBL9403133 0.88 TSHR (0.42) TSHRHPGDCYP3A4POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1282677-C Hydroxyl acrylic acid emulsion with microgel nuclear structure and preparation process and application thereof UNIV SOUTH CHINA TECH (CN) 2006-11-01 CN disclosed