Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5080728 | 1.00 | TSHR (0.44) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL11030313 | 0.98 | TSHR (0.42) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL4603161 | 0.95 | TSHR (0.49) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL996122 | 0.93 | TSHR (0.42) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL11220288 | 0.92 | TSHR (0.46) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL5448469 | 0.92 | TSHR (0.47) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL4585244 | 0.91 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL2577166 | 0.91 | TSHR (0.50) | TSHRALDH1A1THRBPOLBAPEX1 | |
| SCHEMBL5971626 | 0.90 | TSHR (0.58) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL8740553 | 0.89 | TSHR (0.36) | TSHRHPGDALDH1A1CYP3A4THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120019888-A1 | PRIMER COMPOSITION FOR OPTICAL ARTICLES AND OPTICAL ARTICLES | TOKUYAMA CORPORATION (JP) | 2012-01-26 | — | — | US | disclosed |