SCHEMBL10361925

SCHEMBL10361925

Fc1nc(C(F)(F)F)nc(F)c1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10361899 0.81
SCHEMBL9810085 0.78
SCHEMBL10744210 0.77
SCHEMBL2116132 0.74
SCHEMBL10703268 0.72
SCHEMBL9787157 0.72 NOTUM (0.35)
SCHEMBL175478 0.71 ALDH1A1 (0.33)
SCHEMBL11962985 0.70 MEN1 (0.33)
SCHEMBL83209 0.69
SCHEMBL9181490 0.69 ALDH1A1 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0235729-B1 REACTIVE DYES BAYER AG (DE) 1990-12-19 EP disclosed
EP-0203505-B1 DISAZO METAL COMPLEX DYES BAYER AG (DE) 1989-05-24 EP disclosed
EP-0186812-B1 REACTIVE DYES BAYER AG (DE) 1989-01-25 EP disclosed
EP-0192067-B1 DISAZO DYES BAYER AG (DE) 1988-06-01 EP disclosed
EP-0158882-B1 TRIPHENEDIOXAZINE DYES BAYER AG (DE) 1987-12-16 EP disclosed
EP-0235729-A2 Reactive dyes BAYER AG (DE) 1987-09-09 EP disclosed
EP-0128340-B1 REACTIVE DISAZO DYES BAYER AG (DE) 1987-05-27 EP disclosed
EP-0203505-A1 Disazo metal complex dyes BAYER AG (DE) 1986-12-03 EP disclosed
US-4621138-A Triphendioxazine dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1986-11-04 US disclosed
EP-0186812-A2 Reactive dyes BAYER AG (DE) 1986-07-09 EP disclosed
EP-0158882-A2 Triphenedioxazine dyes BAYER AG (DE) 1985-10-23 EP disclosed
EP-0153127-A2 N-aryl-3-aryl-4,5-dihydro-1H-pyrazole-1-carboxamides, processes for their production, insecticidal compositions containing them and methods for combatting insects ROHM AND HAAS COMPANY (US) 1985-08-28 EP disclosed
EP-0139248-A2 Reactive dyes BAYER AG (DE) 1985-05-02 EP disclosed
EP-0128316-A1 Reactive disazo dyes BAYER AG (DE) 1984-12-19 EP disclosed
EP-0128340-A1 Reactive disazo dyes BAYER AG (DE) 1984-12-19 EP disclosed
US-4007164-A FIBER-REACTIVE, CELLULOSE, WOOL BAYER AKTIENGESELLSCHAFT (DT) 1977-02-08 US disclosed