SCHEMBL9810085

SCHEMBL9810085

Fc1nc(C(Cl)(Cl)Cl)nc(F)c1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10361899 0.81
SCHEMBL10361925 0.78
SCHEMBL10772465 0.76
SCHEMBL79695 0.71 CCNB2 (0.31)
SCHEMBL2118504 0.71
SCHEMBL9181490 0.69 ALDH1A1 (0.47)
SCHEMBL83209 0.69
SCHEMBL5673702 0.69
SCHEMBL10711472 0.67 ALDH1A1 (0.44)
SCHEMBL10361857 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0272532-B1 DYESTUFFS BAYER AG (DE) 1991-05-29 EP disclosed
EP-0235729-B1 REACTIVE DYES BAYER AG (DE) 1990-12-19 EP disclosed
EP-0272532-A2 Dyestuffs BAYER AG (DE) 1988-06-29 EP disclosed
US-4716229-A New pyrimidines and a process for the preparation of pyrimidines BAYER AKTIENGESELLSCHAFT (DE) 1987-12-29 US disclosed
EP-0133663-B1 PYRIMIDINES AND A PROCESS FOR THE PREPARATION OF PYRIMIDINES BAYER AG (DE) 1987-04-08 EP disclosed
EP-0125650-B1 REACTIVE DYES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE DYEING AND PRINTING OF SUBSTRATES BAYER AG (DE) 1987-04-01 EP disclosed
EP-0183092-A1 5,6-Dichloro-4-hydroxy-2-trichloromethylpyrimidine BAYER AG (DE) 1986-06-04 EP disclosed
EP-0151939-A2 Pyrimidinediones and dihydroxypyrimidines, and process for the preparation of pyrimidinedones and dihydroxypyrimidines BAYER AG (DE) 1985-08-21 EP disclosed
EP-0139248-A2 Reactive dyes BAYER AG (DE) 1985-05-02 EP disclosed
EP-0133663-A1 Pyrimidines and a process for the preparation of pyrimidines BAYER AG (DE) 1985-03-06 EP disclosed
EP-0125650-A2 Reactive dyes, process for their preparation and their use in the dyeing and printing of substrates BAYER AG (DE) 1984-11-21 EP disclosed