Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | NAMPT | P43490 | 1/20 | 0.55 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10361932 | 0.90 | MAPT (0.66) | MAPTSMN1; SMN2POLBLMNAL3MBTL1 | |
| SCHEMBL10363480 | 0.89 | MAPT (0.80) | MAPTSMN1; SMN2POLBLMNAL3MBTL1 | |
| SCHEMBL10362010 | 0.85 | LMNA (0.66) | MAPTSMN1; SMN2POLBLMNAL3MBTL1 | |
| SCHEMBL10361963 | 0.83 | LMNA (0.70) | MAPTSMN1; SMN2POLBLMNAL3MBTL1 | |
| SCHEMBL10361959 | 0.83 | LMNA (0.62) | MAPTSMN1; SMN2POLBLMNAL3MBTL1 | |
| SCHEMBL10361518 | 0.82 | LMNA (0.61) | MAPTSMN1; SMN2POLBLMNAKMT2A | |
| SCHEMBL10362136 | 0.81 | LMNA (0.56) | MAPTSMN1; SMN2POLBLMNAL3MBTL1 | |
| SCHEMBL10644433 | 0.80 | LMNA (0.82) | MAPTSMN1; SMN2POLBLMNAL3MBTL1 | |
| SCHEMBL10760442 | 0.80 | MGLL (0.63) | MAPTSMN1; SMN2POLBLMNAKMT2A | |
| SCHEMBL10362444 | 0.79 | LMNA (0.60) | MAPTSMN1; SMN2POLBLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207901-B1 | ANTIANAPHYLACTIC AND ANTIBRONCHOSPASTIC N-BENZHYDRYLDIAZACYCLOALKYLALKANANILIDES | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 1990-11-28 | — | — | EP | claimed |
| US-4675319-A | Antianaphylactic and antibronchospastic piperazinyl-(N-substituted phenyl)carboxamides, compositions and use | RECORDATI S. A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1987-06-23 | — | — | US | claimed |
| EP-0207901-A1 | Antianaphylactic and antibronchospastic N-benzhydryldiazacycloalkylalkananilides | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 1987-01-07 | — | — | EP | claimed |
| EP-0207901-B1 | ANTIANAPHYLACTIC AND ANTIBRONCHOSPASTIC N-BENZHYDRYLDIAZACYCLOALKYLALKANANILIDES | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 1990-11-28 | — | — | EP | disclosed |
| US-4675319-A | Antianaphylactic and antibronchospastic piperazinyl-(N-substituted phenyl)carboxamides, compositions and use | RECORDATI S. A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1987-06-23 | — | — | US | disclosed |