Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLM | Q9NP87 | 2/20 | 0.43 |
| ▸ | POLK | Q9UBT6 | 2/20 | 0.43 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.43 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.43 |
| ▸ | TOP1 | P11387 | 3/20 | 0.43 |
| ▸ | TGM2 | P21980 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ITK | Q08881 | 3/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10804942 | 0.86 | KCNA3 (0.51) | TGM2KMT2AGAAITKZDHHC20 | |
| SCHEMBL10806417 | 0.82 | TGM2 (0.49) | TGM2KMT2AGAAITKZDHHC20 | |
| SCHEMBL10818993 | 0.82 | GAA (0.54) | TGM2KMT2AGAAITKZDHHC20 | |
| SCHEMBL10803446 | 0.80 | TGM2 (0.56) | TGM2KMT2AGAAITKZDHHC20 | |
| SCHEMBL10807055 | 0.79 | TGM2 (0.49) | TGM2KMT2AGAAITKZDHHC20 | |
| SCHEMBL10362504 | 0.78 | GAA (0.66) | TGM2KMT2AGAAKDM4EALDH1A1 | |
| SCHEMBL10806562 | 0.77 | TGM2 (0.53) | TGM2KMT2AGAAITKZDHHC20 | |
| SCHEMBL10802603 | 0.77 | KMT2A (0.43) | TGM2KMT2AGAAITKZDHHC20 | |
| SCHEMBL10362443 | 0.77 | GAA (0.49) | TGM2KMT2AGAAITKZDHHC20 | |
| SCHEMBL10803598 | 0.77 | SMN1; SMN2 (0.50) | TGM2KMT2AGAAZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155177-B1 | UNSATURATED CYCLIC AMIDO-SUBSTITUTED ETHER COMPOUNDS AND PREPARATION PROCESS THEREOF | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-10-31 | — | — | EP | disclosed |
| US-4649219-A | CROSSLINKERS, ADHESIVES, PAINTS | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1987-03-10 | — | — | US | disclosed |
| EP-0155177-A2 | Unsaturated cyclic amido-substituted ether compounds and preparation process thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1985-09-18 | — | — | EP | disclosed |