Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ITK | Q08881 | 1/20 | 0.40 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10818993 | 0.93 | GAA (0.54) | GAAKMT2ATGM2KDM4EHTT | |
| SCHEMBL10363161 | 0.89 | TGM2 (0.51) | GAAKMT2ATGM2KDM4EALDH1A1 | |
| SCHEMBL10803446 | 0.86 | TGM2 (0.56) | GAAKMT2ATGM2KDM4EALDH1A1 | |
| SCHEMBL10362504 | 0.86 | GAA (0.66) | GAAKMT2ATGM2KDM4EHTT | |
| SCHEMBL10806216 | 0.83 | TGM2 (0.45) | GAAKMT2ATGM2ITKZDHHC20 | |
| SCHEMBL10804040 | 0.82 | TGM2 (0.45) | GAAKMT2ATGM2KDM4EALDH1A1 | |
| SCHEMBL10807055 | 0.82 | TGM2 (0.49) | GAAKMT2ATGM2KDM4EALDH1A1 | |
| SCHEMBL10364043 | 0.80 | TGM2 (0.50) | GAAKMT2ATGM2KDM4EALDH1A1 | |
| SCHEMBL10806562 | 0.80 | TGM2 (0.53) | GAAKMT2ATGM2KDM4EHTT | |
| SCHEMBL10362346 | 0.80 | ALDH1A1 (0.54) | GAAKMT2ATGM2KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155177-B1 | UNSATURATED CYCLIC AMIDO-SUBSTITUTED ETHER COMPOUNDS AND PREPARATION PROCESS THEREOF | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-10-31 | — | — | EP | disclosed |
| US-4649219-A | CROSSLINKERS, ADHESIVES, PAINTS | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1987-03-10 | — | — | US | disclosed |
| EP-0155177-A2 | Unsaturated cyclic amido-substituted ether compounds and preparation process thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1985-09-18 | — | — | EP | disclosed |