Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TGM2 | P21980 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10808998 | 0.91 | RAB9A (0.53) | RAB9ATGM2TSHRTDP1CYP19A1 | |
| SCHEMBL10362336 | 0.88 | RAB9A (0.48) | RAB9ATGM2TSHRTDP1CYP19A1 | |
| SCHEMBL10363305 | 0.86 | RAB9A (0.52) | RAB9ATGM2MAPTMEN1KMT2A | |
| SCHEMBL10364150 | 0.86 | RAB9A (0.51) | RAB9ATGM2TDP1APEX1ALDH1A1 | |
| SCHEMBL10364059 | 0.85 | RAB9A (0.53) | RAB9ATGM2TDP1CYP19A1APEX1 | |
| SCHEMBL10364064 | 0.85 | RAB9A (0.68) | RAB9ATGM2TDP1MAPTMEN1 | |
| SCHEMBL10363741 | 0.85 | RAB9A (0.50) | RAB9ATGM2TSHRTDP1APEX1 | |
| SCHEMBL10803038 | 0.84 | RAB9A (0.49) | RAB9ATGM2TSHRTDP1CYP19A1 | |
| SCHEMBL10363126 | 0.83 | TGM2 (0.46) | TGM2GAATYR | |
| SCHEMBL10362592 | 0.82 | MAPT (0.55) | RAB9ATGM2APEX1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155177-B1 | UNSATURATED CYCLIC AMIDO-SUBSTITUTED ETHER COMPOUNDS AND PREPARATION PROCESS THEREOF | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-10-31 | — | — | EP | disclosed |
| US-4649219-A | CROSSLINKERS, ADHESIVES, PAINTS | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1987-03-10 | — | — | US | disclosed |
| EP-0155177-A2 | Unsaturated cyclic amido-substituted ether compounds and preparation process thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1985-09-18 | — | — | EP | disclosed |