Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.40 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 3/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | FLT3 | P36888 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10361820 | 0.91 | NCOA1 (0.47) | CYP3A4TDP1PDK2NCOA1NCOA3 | |
| SCHEMBL9399245 | 0.83 | ABL1 (0.47) | PDK2KIF11NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2787589 | 0.75 | CA1 (0.61) | CYP3A4TDP1HSD17B10TAAR1CA12 | |
| SCHEMBL30174378 | 0.74 | KIF11 (0.36) | CYP3A4TDP1HSD17B10TAAR1PDK2 | |
| SCHEMBL9246341 | 0.72 | HSD17B10 (0.63) | CYP3A4TDP1HSD17B10TAAR1NCOA1 | |
| SCHEMBL6742476 | 0.72 | CA12 (0.45) | CYP3A4TDP1HSD17B10TAAR1CA12 | |
| SCHEMBL2787163 | 0.71 | BACE1 (0.53) | CYP3A4TDP1HSD17B10TAAR1PDK2 | |
| SCHEMBL28674704 | 0.70 | TSHR (0.42) | CYP3A4TDP1HSD17B10TAAR1PDK2 | |
| SCHEMBL29118206 | 0.70 | HSD17B10 (0.68) | CYP3A4TDP1HSD17B10TAAR1PDK2 | |
| SCHEMBL29948076 | 0.70 | HSD17B10 (0.60) | CYP3A4TDP1HSD17B10TAAR1NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4978733-A | Polyamide-polyamide-polyimide and polybenzoxazole-polyamide-polyimide polymer having at least one fluorine-containing linking group | HOECHST CELANESE CORP. (US) | 1990-12-18 | — | — | US | disclosed |
| US-4931540-A | POLYIMIDES OR OLIGOMERS; MOLDING MATERIALS, PHOTORESISTS, ADHESIVES; HEAT, OXYGEN RESISTANT | HOECHST CELANESE CORPORATION (US) | 1990-06-05 | — | — | US | disclosed |
| US-4914180-A | Polyamides prepared from 2-(3-aminophenyl)-2-(4-aminophenyl) hexafluoro propane | HOECHST CELANESE CORPORATION (US) | 1990-04-03 | — | — | US | disclosed |