SCHEMBL9399245

SCHEMBL9399245

Oc1ccc(-c2ccccc2C(c2ccccc2-c2ccc(O)cc2)C(F)(F)F)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 2/20 0.47
ABCB1 P08183 2/20 0.47
BCR P11274 2/20 0.47
ESR2 Q92731 4/20 0.47
ESR1 P03372 4/20 0.47
PDK2 Q15119 3/20 0.41
MMP3 P08254 1/20 0.41
BCL2L1 Q07817 1/20 0.41
KIF11 P52732 1/20 0.41
PTPN1 P18031 1/20 0.40
BACE1 P56817 1/20 0.40
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
HPGDS O60760 1/20 0.36
MAPT P10636 1/20 0.36
PKM P14618 1/20 0.36
MAOB P27338 1/20 0.36
RAB9A P51151 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10363232 0.83 CYP3A4 (0.40) PDK2KIF11MEN1NPC1RAB9A
SCHEMBL1758175 0.79 ABL1 (0.54) ABL1ABCB1BCRESR2ESR1
SCHEMBL1513629 0.76 CA1 (0.56) ABL1ABCB1BCRESR2ESR1
SCHEMBL3264500 0.76 ABL1 (0.50) ABL1ABCB1BCRESR2ESR1
SCHEMBL10361820 0.75 NCOA1 (0.47) PDK2MEN1NPC1MAPTMAOB
SCHEMBL9513577 0.74 ABL1 (0.48) ABL1ABCB1BCRESR2ESR1
SCHEMBL9334910 0.74 ACMSD (0.49) PDK2PTPN1MEN1KMT2A
SCHEMBL4432976 0.73 ABL1 (0.76) ABL1ABCB1BCRESR2ESR1
SCHEMBL1649339 0.73 ABL1 (0.76) ABL1ABCB1BCRESR2ESR1
SCHEMBL28292946 0.73 ABL1 (0.47) ABL1ABCB1BCRESR2ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5344981-A Fluorinated monomers useful for preparing fluorinated polyquinoline polymers MAXDEM INCORPORATED (US) 1994-09-06 US disclosed